1xal: Difference between revisions

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[[Image:1xal.png|left|200px]]


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==CRYSTAL STRUCTURE OF STAPHLYOCOCCUS AUREUS 3-DEHYDROQUINATE SYNTHASE (DHQS) IN COMPLEX WITH ZN2+, NAD+ AND CARBAPHOSPHONATE (SOAK)==
The line below this paragraph, containing "STRUCTURE_1xal", creates the "Structure Box" on the page.
<StructureSection load='1xal' size='340' side='right'caption='[[1xal]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1xal]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XAL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XAL FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CRB:[1R-(1ALPHA,3BETA,4ALPHA,5BETA)]-5-(PHOSPHONOMETHYL)-1,3,4-TRIHYDROXYCYCLOHEXANE-1-CARBOXYLIC+ACID'>CRB</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_1xal|  PDB=1xal  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xal OCA], [https://pdbe.org/1xal PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xal RCSB], [https://www.ebi.ac.uk/pdbsum/1xal PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xal ProSAT]</span></td></tr>
 
</table>
===CRYSTAL STRUCTURE OF STAPHLYOCOCCUS AUREUS 3-DEHYDROQUINATE SYNTHASE (DHQS) IN COMPLEX WITH ZN2+, NAD+ AND CARBAPHOSPHONATE (SOAK)===
== Function ==
 
[https://www.uniprot.org/uniprot/AROB_STAAR AROB_STAAR]
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_15465043}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 15465043 is the PubMed ID number.
  <jmolCheckbox>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xa/1xal_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_15465043}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1XAL is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XAL OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xal ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
<ref group="xtra">PMID:15465043</ref><references group="xtra"/>
</StructureSection>
[[Category: 3-dehydroquinate synthase]]
[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Charles, I.]]
[[Category: Charles I]]
[[Category: Dhaliwal, B.]]
[[Category: Dhaliwal B]]
[[Category: Hawkins, A R.]]
[[Category: Hawkins AR]]
[[Category: Leslie, K.]]
[[Category: Leslie K]]
[[Category: Lockyer, M.]]
[[Category: Lockyer M]]
[[Category: Nichols, C E.]]
[[Category: Nichols CE]]
[[Category: Ren, J.]]
[[Category: Ren J]]
[[Category: Stammers, D K.]]
[[Category: Stammers DK]]
[[Category: Aromatic amino acid biosynthesis]]
[[Category: Closed form]]
[[Category: Cyclase]]
[[Category: Dhq]]
[[Category: Domain movement]]
[[Category: Form b]]
[[Category: Lyase]]
[[Category: Sadhq]]
[[Category: Shikimate pathway]]
 
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