1waf: Difference between revisions

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[[Image:1waf.png|left|200px]]


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==DNA POLYMERASE FROM BACTERIOPHAGE RB69==
The line below this paragraph, containing "STRUCTURE_1waf", creates the "Structure Box" on the page.
<StructureSection load='1waf' size='340' side='right'caption='[[1waf]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1waf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_RB69 Escherichia phage RB69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WAF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WAF FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GMP:GUANOSINE'>GMP</scene></td></tr>
{{STRUCTURE_1waf| PDB=1waf |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1waf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1waf OCA], [https://pdbe.org/1waf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1waf RCSB], [https://www.ebi.ac.uk/pdbsum/1waf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1waf ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DPOL_BPR69 DPOL_BPR69] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wa/1waf_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1waf ConSurf].
<div style="clear:both"></div>


===DNA POLYMERASE FROM BACTERIOPHAGE RB69===
==See Also==
 
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_9215631}}, adds the Publication Abstract to the page
[[Category: Escherichia phage RB69]]
(as it appears on PubMed at http://www.pubmed.gov), where 9215631 is the PubMed ID number.
[[Category: Large Structures]]
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[[Category: Karam JD]]
{{ABSTRACT_PUBMED_9215631}}
[[Category: Konigsberg WH]]
 
[[Category: Satter AKMA]]
==About this Structure==
[[Category: Steitz TA]]
1WAF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_rb69 Enterobacteria phage rb69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WAF OCA].
[[Category: Wang CC]]
 
[[Category: Wang J]]
==Reference==
Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69., Wang J, Sattar AK, Wang CC, Karam JD, Konigsberg WH, Steitz TA, Cell. 1997 Jun 27;89(7):1087-99. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9215631 9215631]
[[Category: DNA-directed DNA polymerase]]
[[Category: Enterobacteria phage rb69]]
[[Category: Single protein]]
[[Category: Karam, J D.]]
[[Category: Konigsberg, W H.]]
[[Category: Satter, A K.M A.]]
[[Category: Steitz, T A.]]
[[Category: Wang, C C.]]
[[Category: Wang, J.]]
[[Category: Nucleotidyltransferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 15:01:02 2008''

Latest revision as of 11:47, 14 February 2024

DNA POLYMERASE FROM BACTERIOPHAGE RB69DNA POLYMERASE FROM BACTERIOPHAGE RB69

Structural highlights

1waf is a 2 chain structure with sequence from Escherichia phage RB69. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DPOL_BPR69 This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1waf, resolution 3.20Å

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