1vtm: Difference between revisions

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New page: left|200px<br /><applet load="1vtm" size="450" color="white" frame="true" align="right" spinBox="true" caption="1vtm, resolution 3.5Å" /> '''STRUCTURE OF THE U2 S...
 
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[[Image:1vtm.gif|left|200px]]<br /><applet load="1vtm" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1vtm, resolution 3.5&Aring;" />
'''STRUCTURE OF THE U2 STRAIN OF TOBACCO MOSAIC VIRUS REFINED AT 3.5 ANGSTROMS RESOLUTION USING X-RAY FIBER DIFFRACTION'''<br />


==Overview==
==STRUCTURE OF THE U2 STRAIN OF TOBACCO MOSAIC VIRUS REFINED AT 3.5 ANGSTROMS RESOLUTION USING X-RAY FIBER DIFFRACTION==
The structure of the U2 strain of tobacco mosaic virus (TMV) has been, determined by fiber diffraction methods at 3.5 A resolution, and refined, by a combination of restrained least-squares and molecular dynamics, methods to an R-factor of 0.096. The structure is extremely similar to, that of the common strain of TMV, with the largest differences being in, the protein loop that makes up the inner surface of the virus, and in the, C-terminal region on the outer surface. Differences in the inner loop can, be correlated with differences in the properties of the two viruses.
<StructureSection load='1vtm' size='340' side='right'caption='[[1vtm]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1vtm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Tobacco_mild_green_mosaic_virus Tobacco mild green mosaic virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VTM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VTM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Fiber diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vtm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vtm OCA], [https://pdbe.org/1vtm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vtm RCSB], [https://www.ebi.ac.uk/pdbsum/1vtm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vtm ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CAPSD_TMGMV CAPSD_TMGMV] Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vt/1vtm_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vtm ConSurf].
<div style="clear:both"></div>


==About this Structure==
==See Also==
1VTM is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1VTM OCA].
*[[Tobacco Mosaic Virus|Tobacco Mosaic Virus]]
 
*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
==Reference==
__TOC__
Structure of the U2 strain of tobacco mosaic virus refined at 3.5 A resolution using X-ray fiber diffraction., Pattanayek R, Stubbs G, J Mol Biol. 1992 Nov 20;228(2):516-28. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=1453461 1453461]
</StructureSection>
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Pattanayek, R.]]
[[Category: Tobacco mild green mosaic virus]]
[[Category: Stubbs, G.]]
[[Category: Pattanayek R]]
[[Category: icosahedral virus]]
[[Category: Stubbs G]]
[[Category: virus]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 05:07:59 2007''

Latest revision as of 11:47, 14 February 2024

STRUCTURE OF THE U2 STRAIN OF TOBACCO MOSAIC VIRUS REFINED AT 3.5 ANGSTROMS RESOLUTION USING X-RAY FIBER DIFFRACTIONSTRUCTURE OF THE U2 STRAIN OF TOBACCO MOSAIC VIRUS REFINED AT 3.5 ANGSTROMS RESOLUTION USING X-RAY FIBER DIFFRACTION

Structural highlights

1vtm is a 2 chain structure with sequence from Tobacco mild green mosaic virus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Fiber diffraction, Resolution 3.5Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CAPSD_TMGMV Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1vtm, resolution 3.50Å

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