1unk: Difference between revisions

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-{{Seed}}
-[[Image:1unk.png|left|200px]]
-<!--
+==STRUCTURE OF COLICIN E7 IMMUNITY PROTEIN==
-The line below this paragraph, containing "STRUCTURE_1unk", creates the "Structure Box" on the page.
+<StructureSection load='1unk' size='340' side='right'caption='[[1unk]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1unk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UNK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UNK FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1unk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1unk OCA], [https://pdbe.org/1unk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1unk RCSB], [https://www.ebi.ac.uk/pdbsum/1unk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1unk ProSAT]</span></td></tr>
-{{STRUCTURE_1unk|  PDB=1unk  |  SCENE=  }}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/IMM7_ECOLX IMM7_ECOLX] This protein is able to protect a cell, which harbors the plasmid ColE7 encoding colicin E7, against colicin E7, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity. Dimeric ImmE7 may possess a RNase activity that cleaves its own mRNA at a specific site and thus autoregulates translational expression of the downstream ceiE7 gene as well as degradation of the upstream ceaE7 mRNA.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/un/1unk_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1unk ConSurf].
+<div style="clear:both"></div>
-===STRUCTURE OF COLICIN E7 IMMUNITY PROTEIN===
+==See Also==
+*[[Colicin 3D structures|Colicin 3D structures]]
+*[[Colicin immunity protein 3D structures|Colicin immunity protein 3D structures]]
-<!--
+__TOC__
-The line below this paragraph, {{ABSTRACT_PUBMED_9135159}}, adds the Publication Abstract to the page
+</StructureSection>
-(as it appears on PubMed at http://www.pubmed.gov), where 9135159 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_9135159}}
-==About this Structure==
-UNK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UNK OCA].
-==Reference==
-A novel role of ImmE7 in the autoregulatory expression of the ColE7 operon and identification of possible RNase active sites in the crystal structure of dimeric ImmE7., Hsieh SY, Ko TP, Tseng MY, Ku W, Chak KF, Yuan HS, EMBO J. 1997 Mar 17;16(6):1444-54. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9135159 9135159]
 [[Category: Escherichia coli]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Chak, K F.]]
+[[Category: Chak K-F]]
-[[Category: Hsieh, S Y.]]
+[[Category: Hsieh S-Y]]
-[[Category: Ko, T P.]]
+[[Category: Ko T-P]]
-[[Category: Ku, W Y.]]
+[[Category: Ku W-Y]]
-[[Category: Tseng, M Y.]]
+[[Category: Tseng M-Y]]
-[[Category: Yuan, H S.]]
+[[Category: Yuan HS]]
-[[Category: Dimeric structure]]
-[[Category: Immunity protein]]
-[[Category: Rnase active site]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 09:50:52 2008''