1ubs: Difference between revisions

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-[[Image:1ubs.png|left|200px]]
-{{STRUCTURE_1ubs|  PDB=1ubs  |  SCENE=  }}
+==TRYPTOPHAN SYNTHASE (E.C.4.2.1.20) WITH A MUTATION OF LYS 87->THR IN THE B SUBUNIT AND IN THE PRESENCE OF LIGAND L-SERINE==
+<StructureSection load='1ubs' size='340' side='right'caption='[[1ubs]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-===TRYPTOPHAN SYNTHASE (E.C.4.2.1.20) WITH A MUTATION OF LYS 87->THR IN THE B SUBUNIT AND IN THE PRESENCE OF LIGAND L-SERINE===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1ubs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UBS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UBS FirstGlance]. <br>
-{{ABSTRACT_PUBMED_9201907}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=SER:SERINE'>SER</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ubs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ubs OCA], [https://pdbe.org/1ubs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ubs RCSB], [https://www.ebi.ac.uk/pdbsum/1ubs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ubs ProSAT]</span></td></tr>
-[[1ubs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UBS OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/TRPB_SALTY TRPB_SALTY] The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ub/1ubs_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ubs ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Tryptophan synthase|Tryptophan synthase]]
+*[[Tryptophan synthase 3D structures|Tryptophan synthase 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:009201907</ref><references group="xtra"/>
+[[Category: Large Structures]]
-[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
+[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
-[[Category: Tryptophan synthase]]
+[[Category: Ahmed SA]]
-[[Category: Ahmed, S A.]]
+[[Category: Davies DR]]
-[[Category: Davies, D R.]]
+[[Category: Miles EW]]
-[[Category: Miles, E W.]]
+[[Category: Parris K]]
-[[Category: Parris, K.]]
+[[Category: Rhee S]]
-[[Category: Rhee, S.]]
-[[Category: Lyase-peptide complex]]