1u0c: Difference between revisions

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[[Image:1u0c.png|left|200px]]


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==Y33C Mutant of Homing endonuclease I-CreI==
The line below this paragraph, containing "STRUCTURE_1u0c", creates the "Structure Box" on the page.
<StructureSection load='1u0c' size='340' side='right'caption='[[1u0c]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1u0c]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U0C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U0C FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_1u0c|  PDB=1u0c  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u0c OCA], [https://pdbe.org/1u0c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u0c RCSB], [https://www.ebi.ac.uk/pdbsum/1u0c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u0c ProSAT]</span></td></tr>
 
</table>
===Y33C Mutant of Homing endonuclease I-CreI===
== Function ==
 
[https://www.uniprot.org/uniprot/DNE1_CHLRE DNE1_CHLRE] Endonuclease involved in group I intron homing. Recognizes and cleaves a 19-24 bp palindromic DNA site.
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_15313605}}, adds the Publication Abstract to the page
Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u0/1u0c_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_15313605}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
[[1u0c]] is a 4 chain structure of [[Endonuclease]] with sequence from [http://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U0C OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u0c ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Endonuclease|Endonuclease]]
*[[Endonuclease 3D structures|Endonuclease 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:015313605</ref><references group="xtra"/>
[[Category: Chlamydomonas reinhardtii]]
[[Category: Chlamydomonas reinhardtii]]
[[Category: Bruett, A.]]
[[Category: Large Structures]]
[[Category: Chadsey, M.]]
[[Category: Bruett A]]
[[Category: Engel, A.]]
[[Category: Chadsey M]]
[[Category: Fauce, S.]]
[[Category: Engel A]]
[[Category: Monnat, R.]]
[[Category: Fauce S]]
[[Category: Seligman, L M.]]
[[Category: Monnat R]]
[[Category: Stoddard, B L.]]
[[Category: Seligman LM]]
[[Category: Sussman, D.]]
[[Category: Stoddard BL]]
[[Category: Dna endonuclease i-crei]]
[[Category: Sussman D]]
[[Category: Hydrolase-dna complex]]
[[Category: Protein/dna]]

Latest revision as of 11:43, 14 February 2024

Y33C Mutant of Homing endonuclease I-CreIY33C Mutant of Homing endonuclease I-CreI

Structural highlights

1u0c is a 4 chain structure with sequence from Chlamydomonas reinhardtii. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.5Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DNE1_CHLRE Endonuclease involved in group I intron homing. Recognizes and cleaves a 19-24 bp palindromic DNA site.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1u0c, resolution 2.50Å

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OCA