1tu1: Difference between revisions

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[[Image:1tu1.png|left|200px]]


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==Crystal Structure of Protein of Unknown Function PA94 from Pseudomonas aeruginosa, Putative Regulator==
The line below this paragraph, containing "STRUCTURE_1tu1", creates the "Structure Box" on the page.
<StructureSection load='1tu1' size='340' side='right'caption='[[1tu1]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1tu1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TU1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TU1 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_1tu1|  PDB=1tu1  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tu1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tu1 OCA], [https://pdbe.org/1tu1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tu1 RCSB], [https://www.ebi.ac.uk/pdbsum/1tu1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tu1 ProSAT], [https://www.topsan.org/Proteins/MCSG/1tu1 TOPSAN]</span></td></tr>
 
</table>
===Crystal Structure of Protein of Unknown Function PA94 from Pseudomonas aeruginosa, Putative Regulator===
== Function ==
 
[https://www.uniprot.org/uniprot/EAGT6_PSEAE EAGT6_PSEAE] Plays an essential role in toxin Tse6 delivery to target cells and specifically in the loading of Tse6 onto VgrG1a.<ref>PMID:30177742</ref>
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
1TU1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TU1 OCA].  
Check<jmol>
[[Category: Pseudomonas aeruginosa]]
  <jmolCheckbox>
[[Category: Single protein]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tu/1tu1_consurf.spt"</scriptWhenChecked>
[[Category: Cymborowski, M.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Edwards, A.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Evdokimova, E.]]
  </jmolCheckbox>
[[Category: Joachimiak, A.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tu1 ConSurf].
[[Category: MCSG, Midwest Center for Structural Genomics.]]
<div style="clear:both"></div>
[[Category: Minor, W.]]
== References ==
[[Category: Osipiuk, J.]]
<references/>
[[Category: Savchenko, A.]]
__TOC__
[[Category: Hypothetical protein]]
</StructureSection>
[[Category: Mcsg]]
[[Category: Large Structures]]
[[Category: Midwest center for structural genomic]]
[[Category: Pseudomonas aeruginosa PAO1]]
[[Category: Pa0094]]
[[Category: Cymborowski M]]
[[Category: Protein structure initiative]]
[[Category: Edwards A]]
[[Category: Psi]]
[[Category: Evdokimova E]]
[[Category: Structural genomic]]
[[Category: Joachimiak A]]
 
[[Category: Minor W]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Sep 28 20:35:28 2008''
[[Category: Osipiuk J]]
[[Category: Savchenko A]]

Latest revision as of 11:42, 14 February 2024

Crystal Structure of Protein of Unknown Function PA94 from Pseudomonas aeruginosa, Putative RegulatorCrystal Structure of Protein of Unknown Function PA94 from Pseudomonas aeruginosa, Putative Regulator

Structural highlights

1tu1 is a 2 chain structure with sequence from Pseudomonas aeruginosa PAO1. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.95Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

EAGT6_PSEAE Plays an essential role in toxin Tse6 delivery to target cells and specifically in the loading of Tse6 onto VgrG1a.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. Quentin D, Ahmad S, Shanthamoorthy P, Mougous JD, Whitney JC, Raunser S. Mechanism of loading and translocation of type VI secretion system effector Tse6. Nat Microbiol. 2018 Sep 3. pii: 10.1038/s41564-018-0238-z. doi:, 10.1038/s41564-018-0238-z. PMID:30177742 doi:http://dx.doi.org/10.1038/s41564-018-0238-z

1tu1, resolution 1.95Å

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