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==Structure of NP459575, a predicted glutathione synthase from Salmonella typhimurium==
==Structure of NP459575, a predicted glutathione synthase from Salmonella typhimurium==
<StructureSection load='1tt4' size='340' side='right' caption='[[1tt4]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='1tt4' size='340' side='right'caption='[[1tt4]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1tt4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TT4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TT4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1tt4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TT4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TT4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.801&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tt4 OCA], [http://pdbe.org/1tt4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1tt4 RCSB], [http://www.ebi.ac.uk/pdbsum/1tt4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1tt4 ProSAT], [http://www.topsan.org/Proteins/MCSG/1tt4 TOPSAN]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tt4 OCA], [https://pdbe.org/1tt4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tt4 RCSB], [https://www.ebi.ac.uk/pdbsum/1tt4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tt4 ProSAT], [https://www.topsan.org/Proteins/MCSG/1tt4 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GCS2_SALTY GCS2_SALTY]] ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.[HAMAP-Rule:MF_01609]  
[https://www.uniprot.org/uniprot/GCS2_SALTY GCS2_SALTY] ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.[HAMAP-Rule:MF_01609]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Salty]]
[[Category: Large Structures]]
[[Category: Anderson, W F]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
[[Category: Structural genomic]]
[[Category: Anderson WF]]
[[Category: Miller, D J]]
[[Category: Miller DJ]]
[[Category: Shuvalova, L]]
[[Category: Shuvalova L]]
[[Category: Glutathione synthase]]
[[Category: Mcsg]]
[[Category: Np459575]]
[[Category: PSI, Protein structure initiative]]
[[Category: Unknown function]]

Latest revision as of 11:41, 14 February 2024

Structure of NP459575, a predicted glutathione synthase from Salmonella typhimuriumStructure of NP459575, a predicted glutathione synthase from Salmonella typhimurium

Structural highlights

1tt4 is a 2 chain structure with sequence from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.801Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

GCS2_SALTY ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.[HAMAP-Rule:MF_01609]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1tt4, resolution 2.80Å

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