1t5b: Difference between revisions

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[[Image:1t5b.gif|left|200px]]<br /><applet load="1t5b" size="350" color="white" frame="true" align="right" spinBox="true"
caption="1t5b, resolution 1.40&Aring;" />
'''Structural genomics, A protein from Salmonella typhimurium similar to E. coli acyl carrier protein phosphodiesterase'''<br />


==About this Structure==
==Structural genomics, A protein from Salmonella typhimurium similar to E. coli acyl carrier protein phosphodiesterase==
1T5B is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium] with <scene name='pdbligand=FMN:'>FMN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/[Acyl-carrier-protein]_phosphodiesterase [Acyl-carrier-protein] phosphodiesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.14 3.1.4.14] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T5B OCA].  
<StructureSection load='1t5b' size='340' side='right'caption='[[1t5b]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
[[Category: Salmonella typhimurium]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[1t5b]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T5B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T5B FirstGlance]. <br>
[[Category: [Acyl-carrier-protein] phosphodiesterase]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
[[Category: Collart, F.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
[[Category: Joachimiak, A.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t5b OCA], [https://pdbe.org/1t5b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t5b RCSB], [https://www.ebi.ac.uk/pdbsum/1t5b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t5b ProSAT], [https://www.topsan.org/Proteins/MCSG/1t5b TOPSAN]</span></td></tr>
[[Category: MCSG, Midwest Center for Structural Genomics.]]
</table>
[[Category: Wu, R.]]
== Function ==
[[Category: Zhang, R.]]
[https://www.uniprot.org/uniprot/AZOR_SALTY AZOR_SALTY] Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity.[HAMAP-Rule:MF_01216]
[[Category: FMN]]
== Evolutionary Conservation ==
[[Category: acyl carrier protein phosphodiesterase]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: alpha/beta/alpha sandwich]]
Check<jmol>
[[Category: fmn]]
  <jmolCheckbox>
[[Category: mcsg]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t5/1t5b_consurf.spt"</scriptWhenChecked>
[[Category: midwest center for structural genomics]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: protein structure initiative]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: psi]]
  </jmolCheckbox>
[[Category: structural genomics]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t5b ConSurf].
 
<div style="clear:both"></div>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:10:02 2008''
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
[[Category: Collart F]]
[[Category: Joachimiak A]]
[[Category: Wu R]]
[[Category: Zhang R]]

Latest revision as of 11:36, 14 February 2024

Structural genomics, A protein from Salmonella typhimurium similar to E. coli acyl carrier protein phosphodiesteraseStructural genomics, A protein from Salmonella typhimurium similar to E. coli acyl carrier protein phosphodiesterase

Structural highlights

1t5b is a 2 chain structure with sequence from Salmonella enterica subsp. enterica serovar Typhimurium. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.4Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

AZOR_SALTY Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity.[HAMAP-Rule:MF_01216]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1t5b, resolution 1.40Å

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