1sv0: Difference between revisions

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[[Image:1sv0.png|left|200px]]


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==Crystal Structure Of Yan-SAM/Mae-SAM Complex==
The line below this paragraph, containing "STRUCTURE_1sv0", creates the "Structure Box" on the page.
<StructureSection load='1sv0' size='340' side='right'caption='[[1sv0]], [[Resolution|resolution]] 2.07&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1sv0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SV0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SV0 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.07&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sv0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sv0 OCA], [https://pdbe.org/1sv0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sv0 RCSB], [https://www.ebi.ac.uk/pdbsum/1sv0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sv0 ProSAT]</span></td></tr>
{{STRUCTURE_1sv0|  PDB=1sv0  |  SCENE=  }}
</table>
 
== Function ==
===Crystal Structure Of Yan-SAM/Mae-SAM Complex===
[https://www.uniprot.org/uniprot/POK_DROME POK_DROME] Negative regulator of photoreceptor development that acts antagonistically to the proneural signal mediated by RAS. It acts upstream of SINA to inhibit R7 development.<ref>PMID:1505027</ref> <ref>PMID:1495974</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_15260987}}, adds the Publication Abstract to the page
  <jmolCheckbox>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sv/1sv0_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_15260987}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
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==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sv0 ConSurf].
1SV0 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SV0 OCA].  
<div style="clear:both"></div>
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:15260987</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
[[Category: Bowie, J U.]]
[[Category: Large Structures]]
[[Category: Courey, A J.]]
[[Category: Bowie JU]]
[[Category: Gingery, M.]]
[[Category: Courey AJ]]
[[Category: Hunter, J B.]]
[[Category: Gingery M]]
[[Category: Kim, C A.]]
[[Category: Hunter JB]]
[[Category: Qiao, F.]]
[[Category: Kim CA]]
[[Category: Rebay, I.]]
[[Category: Qiao F]]
[[Category: Sawaya, M R.]]
[[Category: Rebay I]]
[[Category: Song, H.]]
[[Category: Sawaya MR]]
[[Category: Alpha-helix]]
[[Category: Song H]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:16:56 2009''

Latest revision as of 11:34, 14 February 2024

Crystal Structure Of Yan-SAM/Mae-SAM ComplexCrystal Structure Of Yan-SAM/Mae-SAM Complex

Structural highlights

1sv0 is a 4 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.07Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

POK_DROME Negative regulator of photoreceptor development that acts antagonistically to the proneural signal mediated by RAS. It acts upstream of SINA to inhibit R7 development.[1] [2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Lai ZC, Rubin GM. Negative control of photoreceptor development in Drosophila by the product of the yan gene, an ETS domain protein. Cell. 1992 Aug 21;70(4):609-20. PMID:1505027
  2. ↑ Tei H, Nihonmatsu I, Yokokura T, Ueda R, Sano Y, Okuda T, Sato K, Hirata K, Fujita SC, Yamamoto D. pokkuri, a Drosophila gene encoding an E-26-specific (Ets) domain protein, prevents overproduction of the R7 photoreceptor. Proc Natl Acad Sci U S A. 1992 Aug 1;89(15):6856-60. PMID:1495974

1sv0, resolution 2.07Å

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