1sq5: Difference between revisions

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[[Image:1sq5.png|left|200px]]


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==Crystal Structure of E. coli Pantothenate kinase==
The line below this paragraph, containing "STRUCTURE_1sq5", creates the "Structure Box" on the page.
<StructureSection load='1sq5' size='340' side='right'caption='[[1sq5]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1sq5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SQ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SQ5 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=PAU:PANTOTHENOIC+ACID'>PAU</scene></td></tr>
{{STRUCTURE_1sq5|  PDB=1sq5 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sq5 OCA], [https://pdbe.org/1sq5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sq5 RCSB], [https://www.ebi.ac.uk/pdbsum/1sq5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sq5 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/COAA_ECOLI COAA_ECOLI]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sq/1sq5_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sq5 ConSurf].
<div style="clear:both"></div>


===Crystal Structure of E. coli Pantothenate kinase===
==See Also==
 
*[[Pantothenate kinase 3D structures|Pantothenate kinase 3D structures]]
 
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</StructureSection>
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{{ABSTRACT_PUBMED_15136582}}
 
==About this Structure==
1SQ5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SQ5 OCA].
 
==Reference==
The structure of the pantothenate kinase.ADP.pantothenate ternary complex reveals the relationship between the binding sites for substrate, allosteric regulator, and antimetabolites., Ivey RA, Zhang YM, Virga KG, Hevener K, Lee RE, Rock CO, Jackowski S, Park HW, J Biol Chem. 2004 Aug 20;279(34):35622-9. Epub 2004 May 10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15136582 15136582]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Pantothenate kinase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Hevener K]]
[[Category: Hevener, K.]]
[[Category: Ivey RA]]
[[Category: Ivey, R A.]]
[[Category: Jackowski S]]
[[Category: Jackowski, S.]]
[[Category: Lee RE]]
[[Category: Lee, R E.]]
[[Category: Park H-W]]
[[Category: Park, H W.]]
[[Category: Rock CO]]
[[Category: Rock, C O.]]
[[Category: Virga KG]]
[[Category: Virga, K G.]]
[[Category: Zhang Y-M]]
[[Category: Zhang, Y M.]]
[[Category: P-loop]]
 
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