1sg9: Difference between revisions

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-[[Image:1sg9.gif|left|200px]]
- {{Structure
+==Crystal structure of Thermotoga maritima protein HEMK, an N5-glutamine methyltransferase==
-|PDB= 1sg9 |SIZE=350|CAPTION= <scene name='initialview01'>1sg9</scene>, resolution 2.30&Aring;
+<StructureSection load='1sg9' size='340' side='right'caption='[[1sg9]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND= <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>
+<table><tr><td colspan='2'>[[1sg9]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SG9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SG9 FirstGlance]. <br>
-|ACTIVITY=
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-|GENE=
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLN:GLUTAMINE'>GLN</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
-|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK11805 PRK11805], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG2890 HemK]</span>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sg9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sg9 OCA], [https://pdbe.org/1sg9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sg9 RCSB], [https://www.ebi.ac.uk/pdbsum/1sg9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sg9 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1sg9 TOPSAN]</span></td></tr>
-|RELATEDENTRY=
+</table>
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sg9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sg9 OCA], [http://www.ebi.ac.uk/pdbsum/1sg9 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1sg9 RCSB]</span>
+== Function ==
-}}
+[https://www.uniprot.org/uniprot/PRMC_THEMA PRMC_THEMA] Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
+== Evolutionary Conservation ==
-'''Crystal structure of Thermotoga maritima protein HEMK, an N5-glutamine methyltransferase'''
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
-==About this Structure==
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sg/1sg9_consurf.spt"</scriptWhenChecked>
-SG9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SG9 OCA].
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-[[Category: Single protein]]
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sg9 ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Thermotoga maritima]]
-[[Category: Agarwal, R.]]
+[[Category: Agarwal R]]
-[[Category: Burley, S K.]]
+[[Category: Burley SK]]
-[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
+[[Category: Swaminathan S]]
-[[Category: Swaminathan, S.]]
-[[Category: hemk protein]]
-[[Category: hypothetical protein]]
-[[Category: new york structural genomix research consortium]]
-[[Category: nysgxrc]]
-[[Category: protein structure initiative]]
-[[Category: psi]]
-[[Category: structural genomic]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:41:36 2008''