1scb: Difference between revisions

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-[[Image:1scb.png|left|200px]]
-<!--
+==ENZYME CRYSTAL STRUCTURE IN A NEAT ORGANIC SOLVENT==
-The line below this paragraph, containing "STRUCTURE_1scb", creates the "Structure Box" on the page.
+<StructureSection load='1scb' size='340' side='right'caption='[[1scb]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1scb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SCB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SCB FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CCN:ACETONITRILE'>CCN</scene></td></tr>
-{{STRUCTURE_1scb|  PDB=1scb  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1scb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1scb OCA], [https://pdbe.org/1scb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1scb RCSB], [https://www.ebi.ac.uk/pdbsum/1scb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1scb ProSAT]</span></td></tr>
+</table>
-===ENZYME CRYSTAL STRUCTURE IN A NEAT ORGANIC SOLVENT===
+== Function ==
+[https://www.uniprot.org/uniprot/SUBC_BACLI SUBC_BACLI] Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides (Ref.4, PubMed:11109488). Shows high specificity for aromatic and hydrophobic amino acids in the P1 substrate position (PubMed:11109488). May play an important role in the degradation of feather keratin (PubMed:11109488).<ref>PMID:11109488</ref> <ref>PMID:4967581</ref>
+== Evolutionary Conservation ==
-<!--
+[[Image:Consurf_key_small.gif|200px|right]]
-The line below this paragraph, {{ABSTRACT_PUBMED_8378343}}, adds the Publication Abstract to the page
+Check<jmol>
-(as it appears on PubMed at http://www.pubmed.gov), where 8378343 is the PubMed ID number.
+  <jmolCheckbox>
--->
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sc/1scb_consurf.spt"</scriptWhenChecked>
-{{ABSTRACT_PUBMED_8378343}}
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
-==About this Structure==
+  </jmolCheckbox>
-[[1scb]] is a 1 chain structure of [[Subtilisin]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SCB OCA].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1scb ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Subtilisin]]
+*[[Subtilisin 3D structures|Subtilisin 3D structures]]
+== References ==
-==Reference==
+<references/>
-<ref group="xtra">PMID:8378343</ref><references group="xtra"/>
+__TOC__
+</StructureSection>
 [[Category: Bacillus licheniformis]]
-[[Category: Subtilisin]]
+[[Category: Large Structures]]
-[[Category: Fitzpatrick, P A.]]
+[[Category: Fitzpatrick PA]]
-[[Category: Klibanov, A M.]]
+[[Category: Klibanov AM]]
-[[Category: Ringe, D.]]
+[[Category: Ringe D]]
-[[Category: Steinmetz, A C.U.]]
+[[Category: Steinmetz ACU]]
-[[Category: Serine protease]]