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[[Image:1s7h.png|left|200px]]


{{STRUCTURE_1s7h|  PDB=1s7h  |  SCENE=  }}
==Structural Genomics, 2.2A crystal structure of protein YKOF from Bacillus subtilis==
 
<StructureSection load='1s7h' size='340' side='right'caption='[[1s7h]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
===Structural Genomics, 2.2A crystal structure of protein YKOF from Bacillus subtilis===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1s7h]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S7H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S7H FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s7h OCA], [https://pdbe.org/1s7h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s7h RCSB], [https://www.ebi.ac.uk/pdbsum/1s7h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s7h ProSAT], [https://www.topsan.org/Proteins/MCSG/1s7h TOPSAN]</span></td></tr>
[[1s7h]] is a 4 chain structure of [[YKOF]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S7H OCA].  
</table>
 
== Function ==
==See Also==
[https://www.uniprot.org/uniprot/YKOF_BACSU YKOF_BACSU] Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Binds thiamine via its HMP moiety.<ref>PMID:12376536</ref> <ref>PMID:16291685</ref>
*[[YKOF|YKOF]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Dementieva, I.]]
[[Category: Large Structures]]
[[Category: Joachimiak, A.]]
[[Category: Dementieva I]]
[[Category: Lezondra, L.]]
[[Category: Joachimiak A]]
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Category: Lezondra L]]
[[Category: Moy, S.]]
[[Category: Moy S]]
[[Category: Zhang, R.]]
[[Category: Zhang R]]
[[Category: Alpha-beta-beta-alpha sandwich]]
[[Category: Mcsg]]
[[Category: Midwest center for structural genomic]]
[[Category: Protein structure initiative]]
[[Category: Protein ykof]]
[[Category: Psi]]
[[Category: Structural genomic]]
[[Category: Unknown function]]

Latest revision as of 11:28, 14 February 2024

Structural Genomics, 2.2A crystal structure of protein YKOF from Bacillus subtilisStructural Genomics, 2.2A crystal structure of protein YKOF from Bacillus subtilis

Structural highlights

1s7h is a 4 chain structure with sequence from Bacillus subtilis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

YKOF_BACSU Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Binds thiamine via its HMP moiety.[1] [2]

References

  1. ↑ Rodionov DA, Vitreschak AG, Mironov AA, Gelfand MS. Comparative genomics of thiamin biosynthesis in procaryotes. New genes and regulatory mechanisms. J Biol Chem. 2002 Dec 13;277(50):48949-59. Epub 2002 Oct 9. PMID:12376536 doi:http://dx.doi.org/10.1074/jbc.M208965200
  2. ↑ Schyns G, Potot S, Geng Y, Barbosa TM, Henriques A, Perkins JB. Isolation and characterization of new thiamine-deregulated mutants of Bacillus subtilis. J Bacteriol. 2005 Dec;187(23):8127-36. PMID:16291685 doi:http://dx.doi.org/187/23/8127

1s7h, resolution 2.20Å

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