1s1j: Difference between revisions

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-{{Seed}}
-[[Image:1s1j.png|left|200px]]
-<!--
+==Crystal Structure of ZipA in complex with indoloquinolizin inhibitor 1==
-The line below this paragraph, containing "STRUCTURE_1s1j", creates the "Structure Box" on the page.
+<StructureSection load='1s1j' size='340' side='right'caption='[[1s1j]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1s1j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S1J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S1J FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.18&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IQZ:(12BS)-1,2,3,4,12,12B-HEXAHYDROINDOLO[2,3-A]QUINOLIZIN-7(6H)-ONE'>IQZ</scene></td></tr>
-{{STRUCTURE_1s1j|  PDB=1s1j  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s1j OCA], [https://pdbe.org/1s1j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s1j RCSB], [https://www.ebi.ac.uk/pdbsum/1s1j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s1j ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ZIPA_ECOLI ZIPA_ECOLI] Interacts directly with the cell division protein FtsZ. Probable receptor for the septal ring structure, may anchor it to the inner-membrane.[HAMAP-Rule:MF_00509]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s1/1s1j_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1s1j ConSurf].
+<div style="clear:both"></div>
-===Crystal Structure of ZipA in complex with indoloquinolizin inhibitor 1===
+==See Also==
+*[[Cell division protein 3D structures|Cell division protein 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_15006376}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 15006376 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_15006376}}
-==About this Structure==
-S1J is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S1J OCA].
-==Reference==
-Design and synthesis of indolo[2,3-a]quinolizin-7-one inhibitors of the ZipA-FtsZ interaction., Jennings LD, Foreman KW, Rush TS 3rd, Tsao DH, Mosyak L, Li Y, Sukhdeo MN, Ding W, Dushin EG, Kenny CH, Moghazeh SL, Petersen PJ, Ruzin AV, Tuckman M, Sutherland AG, Bioorg Med Chem Lett. 2004 Mar 22;14(6):1427-31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15006376 15006376]
 [[Category: Escherichia coli]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Ding, W.]]
+[[Category: Ding W]]
-[[Category: Dushin, E G.]]
+[[Category: Dushin EG]]
-[[Category: Foreman, K W.]]
+[[Category: Foreman KW]]
-[[Category: III, T S.Rush.]]
+[[Category: Jenning LD]]
-[[Category: Jenning, L D.]]
+[[Category: Kenney CH]]
-[[Category: Kenney, C H.]]
+[[Category: Li Y]]
-[[Category: Li, Y.]]
+[[Category: Moghazeh SL]]
-[[Category: Moghazeh, S L.]]
+[[Category: Mosyak L]]
-[[Category: Mosyak, L.]]
+[[Category: Peterson PJ]]
-[[Category: Peterson, P J.]]
+[[Category: Rush III TS]]
-[[Category: Ruzin, A V.]]
+[[Category: Ruzin AV]]
-[[Category: Sukhdeo, M N.]]
+[[Category: Sukhdeo MN]]
-[[Category: Sutherland, A G.]]
+[[Category: Sutherland AG]]
-[[Category: Tsao, D H.]]
+[[Category: Tsao DH]]
-[[Category: Tuckman, M.]]
+[[Category: Tuckman M]]
-[[Category: Cell cycle]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 01:52:28 2008''