1ry1: Difference between revisions

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-[[Image:1ry1.png|left|200px]]
-{{STRUCTURE_1ry1|  PDB=1ry1  |  SCENE=  }}
+==Structure of the signal recognition particle interacting with the elongation-arrested ribosome==
+<SX load='1ry1' size='340' side='right' viewer='molstar' caption='[[1ry1]], [[Resolution|resolution]] 12.00&Aring;' scene=''>
-===Structure of the signal recognition particle interacting with the elongation-arrested ribosome===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1ry1]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Canis_lupus_familiaris Canis lupus familiaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RY1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RY1 FirstGlance]. <br>
-{{ABSTRACT_PUBMED_14985753}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 12&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CCC:CYTIDINE-5-PHOSPHATE-2,3-CYCLIC+PHOSPHATE'>CCC</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ry1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ry1 OCA], [https://pdbe.org/1ry1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ry1 RCSB], [https://www.ebi.ac.uk/pdbsum/1ry1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ry1 ProSAT]</span></td></tr>
-[[1ry1]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus], [http://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus] and [http://en.wikipedia.org/wiki/Tursiops_truncatus Tursiops truncatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RY1 OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/SRP09_HUMAN SRP09_HUMAN] Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ry/1ry1_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ry1 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Avidin|Avidin]]
+*[[Avidin 3D structures|Avidin 3D structures]]
-*[[Signal recognition particle protein|Signal recognition particle protein]]
+*[[Signal recognition particle 3D structures|Signal recognition particle 3D structures]]
+__TOC__
-==Reference==
+</SX>
-<ref group="xtra">PMID:014985753</ref><references group="xtra"/>
+[[Category: Canis lupus familiaris]]
-[[Category: Homo sapiens]]
+[[Category: Large Structures]]
-[[Category: Mus musculus]]
+[[Category: Becker T]]
-[[Category: Thermus aquaticus]]
+[[Category: Beckmann R]]
-[[Category: Tursiops truncatus]]
+[[Category: Frank J]]
-[[Category: Becker, T.]]
+[[Category: Grassucci RA]]
-[[Category: Beckmann, R.]]
+[[Category: Halic M]]
-[[Category: Frank, J.]]
+[[Category: Pool MR]]
-[[Category: Grassucci, R A.]]
+[[Category: Spahn CM]]
-[[Category: Halic, M.]]
-[[Category: Pool, M R.]]
-[[Category: Spahn, C M.]]
-[[Category: Rna binding]]
-[[Category: Signal recognition particle]]
-[[Category: Translation]]