1rsd: Difference between revisions

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-[[Image:1rsd.png|left|200px]]
-{{STRUCTURE_1rsd|  PDB=1rsd  |  SCENE=  }}
+==DHNA complex with 3-(5-Amino-7-hydroxy-[1,2,3]triazolo[4,5-d]pyrimidin-2-yl)-N-[2-(2-hydroxymethyl-phenylsulfanyl)-benzyl]-benzamide==
+<StructureSection load='1rsd' size='340' side='right'caption='[[1rsd]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-===DHNA complex with 3-(5-Amino-7-hydroxy-[1,2,3]triazolo[4,5-d]pyrimidin-2-yl)-N-[2-(2-hydroxymethyl-phenylsulfanyl)-benzyl]-benzamide===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1rsd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RSD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RSD FirstGlance]. <br>
-{{ABSTRACT_PUBMED_15027862}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PSB:3-(5-AMINO-7-HYDROXY-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-2-YL)-N-[2-(2-(HYDROXYMETHYL-PHENYLSULFANYL)-BENZYL]-BENZAMIDE'>PSB</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rsd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rsd OCA], [https://pdbe.org/1rsd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rsd RCSB], [https://www.ebi.ac.uk/pdbsum/1rsd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rsd ProSAT]</span></td></tr>
-[[1rsd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RSD OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/FOLB_STAAU FOLB_STAAU] Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rs/1rsd_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rsd ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Aldolase|Aldolase]]
+*[[Aldolase 3D structures|Aldolase 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:015027862</ref><references group="xtra"/>
+[[Category: Large Structures]]
-[[Category: Dihydroneopterin aldolase]]
 [[Category: Staphylococcus aureus]]
-[[Category: Betz, S F.]]
+[[Category: Betz SF]]
-[[Category: Beutel, B A.]]
+[[Category: Beutel BA]]
-[[Category: Condroski, K R.]]
+[[Category: Condroski KR]]
-[[Category: Harlan, J E.]]
+[[Category: Harlan JE]]
-[[Category: Jakob, C G.]]
+[[Category: Jakob CG]]
-[[Category: Lerner, C G.]]
+[[Category: Lerner CG]]
-[[Category: Magdalinos, P.]]
+[[Category: Magdalinos P]]
-[[Category: McCall, J O.]]
+[[Category: McCall JO]]
-[[Category: Meadows, R P.]]
+[[Category: Meadows RP]]
-[[Category: Merrick, S M.]]
+[[Category: Merrick SM]]
-[[Category: Nienaber, V L.]]
+[[Category: Nienaber VL]]
-[[Category: Sanders, W J.]]
+[[Category: Sanders WJ]]
-[[Category: Severin, J M.]]
+[[Category: Severin JM]]
-[[Category: Stamper, G F.]]
+[[Category: Stamper GF]]
-[[Category: Stoll, V S.]]
+[[Category: Stoll VS]]
-[[Category: Swanson, S J.]]
+[[Category: Swanson SJ]]
-[[Category: Wagner, R.]]
+[[Category: Wagner R]]
-[[Category: Walter, K A.]]
+[[Category: Walter KA]]
-[[Category: 8-dihydroneopterin aldolase]]
-[[Category: Dhna]]
-[[Category: Lyase]]