1roc: Difference between revisions

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[[Image:1roc.png|left|200px]]


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==Crystal structure of the histone deposition protein Asf1==
The line below this paragraph, containing "STRUCTURE_1roc", creates the "Structure Box" on the page.
<StructureSection load='1roc' size='340' side='right'caption='[[1roc]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1roc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ROC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ROC FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene></td></tr>
{{STRUCTURE_1roc| PDB=1roc |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1roc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1roc OCA], [https://pdbe.org/1roc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1roc RCSB], [https://www.ebi.ac.uk/pdbsum/1roc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1roc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ASF1_YEAST ASF1_YEAST] Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Facilitates histone deposition through both replication-dependent and replication-independent chromatin assembly pathways. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with the HIR complex to promote replication-independent chromatin assembly, which may occur during transcription and DNA repair. May be required for the maintenance of a subset of replication elongation factors, including DNA polymerase epsilon, the RFC complex and PCNA, at stalled replication forks. Also required for acetylation of histone H3 on 'Lys-9' and 'Lys-56'.<ref>PMID:9290207</ref> <ref>PMID:10591219</ref> <ref>PMID:11412995</ref> <ref>PMID:11331602</ref> <ref>PMID:11731479</ref> <ref>PMID:11731480</ref> <ref>PMID:11404324</ref> <ref>PMID:11172707</ref> <ref>PMID:11856374</ref> <ref>PMID:11756556</ref> <ref>PMID:12093919</ref> <ref>PMID:14585955</ref> <ref>PMID:15071494</ref> <ref>PMID:15452122</ref> <ref>PMID:15175160</ref> <ref>PMID:15542829</ref> <ref>PMID:15542840</ref> <ref>PMID:15766286</ref> <ref>PMID:16303565</ref> <ref>PMID:15821127</ref> <ref>PMID:15901673</ref> <ref>PMID:16020781</ref> <ref>PMID:16143623</ref> <ref>PMID:16039596</ref> <ref>PMID:15632066</ref> <ref>PMID:15891116</ref> <ref>PMID:16141196</ref> <ref>PMID:15840725</ref> <ref>PMID:16815704</ref> <ref>PMID:16936140</ref> <ref>PMID:16582440</ref> <ref>PMID:16407267</ref> <ref>PMID:17046836</ref> <ref>PMID:16678113</ref> <ref>PMID:16501045</ref> <ref>PMID:16627621</ref> <ref>PMID:17107956</ref> <ref>PMID:17320445</ref> <ref>PMID:14680630</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ro/1roc_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1roc ConSurf].
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===Crystal structure of the histone deposition protein Asf1===
==See Also==
 
*[[Anti-silencing factor|Anti-silencing factor]]
 
*[[Anti-silencing factor 3D structures|Anti-silencing factor 3D structures]]
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== References ==
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(as it appears on PubMed at http://www.pubmed.gov), where 14680630 is the PubMed ID number.
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</StructureSection>
{{ABSTRACT_PUBMED_14680630}}
[[Category: Large Structures]]
 
==About this Structure==
1ROC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ROC OCA].
 
==Reference==
Structure and function of the conserved core of histone deposition protein Asf1., Daganzo SM, Erzberger JP, Lam WM, Skordalakes E, Zhang R, Franco AA, Brill SJ, Adams PD, Berger JM, Kaufman PD, Curr Biol. 2003 Dec 16;13(24):2148-58. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14680630 14680630]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Single protein]]
[[Category: Adams PD]]
[[Category: Adams, P D.]]
[[Category: Berger JM]]
[[Category: Berger, J M.]]
[[Category: Brill SJ]]
[[Category: Brill, S J.]]
[[Category: Daganzo SM]]
[[Category: Daganzo, S M.]]
[[Category: Erzberger JP]]
[[Category: Erzberger, J P.]]
[[Category: Franco AA]]
[[Category: Franco, A A.]]
[[Category: Kaufman PD]]
[[Category: Kaufman, P D.]]
[[Category: Lam WM]]
[[Category: Lam, W M.]]
[[Category: Skordalakes E]]
[[Category: Skordalakes, E.]]
[[Category: Zhang R]]
[[Category: Zhang, R.]]
[[Category: Beta-sandwich]]
 
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