1rjf: Difference between revisions

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[[Image:1rjf.png|left|200px]]


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==Structure of PPM1, a leucine carboxy methyltransferase involved in the regulation of protein phosphatase 2A activity==
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<StructureSection load='1rjf' size='340' side='right'caption='[[1rjf]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1rjf]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RJF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RJF FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
{{STRUCTURE_1rjf|  PDB=1rjf  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rjf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rjf OCA], [https://pdbe.org/1rjf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rjf RCSB], [https://www.ebi.ac.uk/pdbsum/1rjf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rjf ProSAT]</span></td></tr>
 
</table>
===Structure of PPM1, a leucine carboxy methyltransferase involved in the regulation of protein phosphatase 2A activity===
== Function ==
 
[https://www.uniprot.org/uniprot/LCMT1_YEAST LCMT1_YEAST] Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues. Acts on the two major protein phosphatase 2A catalytic subunits, PPH21 and PPH22.<ref>PMID:11060018</ref> <ref>PMID:11697862</ref>  
 
== Evolutionary Conservation ==
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rj/1rjf_consurf.spt"</scriptWhenChecked>
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==About this Structure==
  </jmolCheckbox>
1RJF is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RJF OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rjf ConSurf].
 
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==Reference==
== References ==
<ref group="xtra">PMID:14660564</ref><references group="xtra"/>
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Bettache, N.]]
[[Category: Bettache N]]
[[Category: Blondeau, K.]]
[[Category: Blondeau K]]
[[Category: Collinet, B.]]
[[Category: Collinet B]]
[[Category: Graille, M.]]
[[Category: Graille M]]
[[Category: Janin, J.]]
[[Category: Janin J]]
[[Category: Leulliot, N.]]
[[Category: Leulliot N]]
[[Category: Poupon, A.]]
[[Category: Poupon A]]
[[Category: Quevillon-Cheruel, S.]]
[[Category: Quevillon-Cheruel S]]
[[Category: Sierra-Gallay, I L.de La.]]
[[Category: Sorel I]]
[[Category: Sorel, I.]]
[[Category: De La Sierra-Gallay IL]]
[[Category: Tilbeurgh, H van.]]
[[Category: Van Tilbeurgh H]]
[[Category: Sam dependent methyltransferase]]
 
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