1rj9: Difference between revisions

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[[Image:1rj9.png|left|200px]]


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==Structure of the heterodimer of the conserved GTPase domains of the Signal Recognition Particle (Ffh) and Its Receptor (FtsY)==
The line below this paragraph, containing "STRUCTURE_1rj9", creates the "Structure Box" on the page.
<StructureSection load='1rj9' size='340' side='right'caption='[[1rj9]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1rj9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RJ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RJ9 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GCP:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>GCP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_1rj9| PDB=1rj9 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rj9 OCA], [https://pdbe.org/1rj9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rj9 RCSB], [https://www.ebi.ac.uk/pdbsum/1rj9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rj9 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FTSY_THEAQ FTSY_THEAQ] Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rj/1rj9_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rj9 ConSurf].
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===Structure of the heterodimer of the conserved GTPase domains of the Signal Recognition Particle (Ffh) and Its Receptor (FtsY)===
==See Also==
 
*[[Signal recognition particle 3D structures|Signal recognition particle 3D structures]]
 
*[[Signal recognition particle receptor 3D structures|Signal recognition particle receptor 3D structures]]
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_14724630}}
 
==About this Structure==
1RJ9 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RJ9 OCA].
 
==Reference==
Substrate twinning activates the signal recognition particle and its receptor., Egea PF, Shan SO, Napetschnig J, Savage DF, Walter P, Stroud RM, Nature. 2004 Jan 15;427(6971):215-21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14724630 14724630]
[[Category: Protein complex]]
[[Category: Thermus aquaticus]]
[[Category: Thermus aquaticus]]
[[Category: Egea, P F.]]
[[Category: Egea PF]]
[[Category: Napetschnig, J.]]
[[Category: Napetschnig J]]
[[Category: Savage, D F.]]
[[Category: Savage DF]]
[[Category: Shan, S O.]]
[[Category: Shan SO]]
[[Category: Stroud, R M.]]
[[Category: Stroud RM]]
[[Category: Walter, P.]]
[[Category: Walter P]]
[[Category: Heterodimer]]
[[Category: Nucleotide twinning]]
[[Category: Protein-protein complex]]
[[Category: Srp-gtpase domain]]
 
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