1rj9: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
m Protected "1rj9" [edit=sysop:move=sysop]
No edit summary
 
(8 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:1rj9.png|left|200px]]


{{STRUCTURE_1rj9|  PDB=1rj9  |  SCENE=  }}
==Structure of the heterodimer of the conserved GTPase domains of the Signal Recognition Particle (Ffh) and Its Receptor (FtsY)==
 
<StructureSection load='1rj9' size='340' side='right'caption='[[1rj9]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
===Structure of the heterodimer of the conserved GTPase domains of the Signal Recognition Particle (Ffh) and Its Receptor (FtsY)===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1rj9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RJ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RJ9 FirstGlance]. <br>
{{ABSTRACT_PUBMED_14724630}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GCP:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>GCP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rj9 OCA], [https://pdbe.org/1rj9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rj9 RCSB], [https://www.ebi.ac.uk/pdbsum/1rj9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rj9 ProSAT]</span></td></tr>
[[1rj9]] is a 2 chain structure of [[Signal recognition particle protein]] with sequence from [http://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RJ9 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/FTSY_THEAQ FTSY_THEAQ] Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rj/1rj9_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rj9 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Signal recognition particle protein|Signal recognition particle protein]]
*[[Signal recognition particle 3D structures|Signal recognition particle 3D structures]]
 
*[[Signal recognition particle receptor 3D structures|Signal recognition particle receptor 3D structures]]
==Reference==
__TOC__
<ref group="xtra">PMID:014724630</ref><ref group="xtra">PMID:016299512</ref><references group="xtra"/>
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermus aquaticus]]
[[Category: Thermus aquaticus]]
[[Category: Egea, P F.]]
[[Category: Egea PF]]
[[Category: Napetschnig, J.]]
[[Category: Napetschnig J]]
[[Category: Savage, D F.]]
[[Category: Savage DF]]
[[Category: Shan, S O.]]
[[Category: Shan SO]]
[[Category: Stroud, R M.]]
[[Category: Stroud RM]]
[[Category: Walter, P.]]
[[Category: Walter P]]
[[Category: Heterodimer]]
[[Category: Nucleotide twinning]]
[[Category: Protein transport]]
[[Category: Protein-protein complex]]
[[Category: Srp-gtpase domain]]

Latest revision as of 11:23, 14 February 2024

Structure of the heterodimer of the conserved GTPase domains of the Signal Recognition Particle (Ffh) and Its Receptor (FtsY)Structure of the heterodimer of the conserved GTPase domains of the Signal Recognition Particle (Ffh) and Its Receptor (FtsY)

Structural highlights

1rj9 is a 2 chain structure with sequence from Thermus aquaticus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

FTSY_THEAQ Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1rj9, resolution 1.90Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=1rj9&oldid=4054397"