1r8c: Difference between revisions

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[[Image:1r8c.png|left|200px]]


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==Crystal Structures of an Archaeal Class I CCA-Adding Enzyme and Its Nucleotide==
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<StructureSection load='1r8c' size='340' side='right'caption='[[1r8c]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1r8c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R8C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R8C FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=UTP:URIDINE+5-TRIPHOSPHATE'>UTP</scene></td></tr>
{{STRUCTURE_1r8c| PDB=1r8c |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r8c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r8c OCA], [https://pdbe.org/1r8c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r8c RCSB], [https://www.ebi.ac.uk/pdbsum/1r8c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r8c ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CCA_ARCFU CCA_ARCFU] Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.<ref>PMID:14592988</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r8/1r8c_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r8c ConSurf].
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===Crystal Structures of an Archaeal Class I CCA-Adding Enzyme and Its Nucleotide===
==See Also==
 
*[[CCA-adding enzyme 3D structures|CCA-adding enzyme 3D structures]]
 
== References ==
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{{ABSTRACT_PUBMED_14636575}}
 
==About this Structure==
1R8C is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R8C OCA].
 
==Reference==
<ref group="xtra">PMID:14636575</ref><references group="xtra"/>
[[Category: Archaeoglobus fulgidus]]
[[Category: Archaeoglobus fulgidus]]
[[Category: TRNA adenylyltransferase]]
[[Category: Large Structures]]
[[Category: Li, F.]]
[[Category: Li F]]
[[Category: Steitz, T A.]]
[[Category: Steitz TA]]
[[Category: Wang, J.]]
[[Category: Wang J]]
[[Category: Weiner, A M.]]
[[Category: Weiner AM]]
[[Category: Xiong, Y.]]
[[Category: Xiong Y]]
[[Category: Cca adding enzyme]]
[[Category: Incoming nucleotide]]
[[Category: Nucleotidyltransferase]]
 
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