1r6o: Difference between revisions

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[[Image:1r6o.png|left|200px]]


{{STRUCTURE_1r6o|  PDB=1r6o  |  SCENE=  }}
==ATP-dependent Clp protease ATP-binding subunit clpA/ATP-dependent Clp protease adaptor protein clpS==
 
<StructureSection load='1r6o' size='340' side='right'caption='[[1r6o]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
===ATP-dependent Clp protease ATP-binding subunit clpA/ATP-dependent Clp protease adaptor protein clpS===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1r6o]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R6O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R6O FirstGlance]. <br>
{{ABSTRACT_PUBMED_15037248}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=Y1:YTTRIUM+ION'>Y1</scene>, <scene name='pdbligand=YBT:BIS-(2-HYDROXYETHYL)AMINO-TRIS(HYDROXYMETHYL)METHANE+YTTRIUM'>YBT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r6o OCA], [https://pdbe.org/1r6o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r6o RCSB], [https://www.ebi.ac.uk/pdbsum/1r6o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r6o ProSAT]</span></td></tr>
[[1r6o]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R6O OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/CLPS_ECOLI CLPS_ECOLI] Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r6/1r6o_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r6o ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Clp Protease|Clp Protease]]
*[[ATP-dependent Clp protease adaptor protein 3D structures|ATP-dependent Clp protease adaptor protein 3D structures]]
 
*[[Heat Shock Protein structures|Heat Shock Protein structures]]
==Reference==
__TOC__
<ref group="xtra">PMID:015037248</ref><references group="xtra"/>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Esser, L.]]
[[Category: Large Structures]]
[[Category: Guo, F.]]
[[Category: Esser L]]
[[Category: Maurizi, M R.]]
[[Category: Guo F]]
[[Category: Singh, S K.]]
[[Category: Maurizi MR]]
[[Category: Xia, D.]]
[[Category: Singh SK]]
[[Category: Aaa+]]
[[Category: Xia D]]
[[Category: Binding mechanism]]
[[Category: Clpa]]
[[Category: Clp]]
[[Category: Crystal]]
[[Category: Hydrolase]]
[[Category: N-terminal domain]]

Latest revision as of 11:20, 14 February 2024

ATP-dependent Clp protease ATP-binding subunit clpA/ATP-dependent Clp protease adaptor protein clpSATP-dependent Clp protease ATP-binding subunit clpA/ATP-dependent Clp protease adaptor protein clpS

Structural highlights

1r6o is a 4 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.25Å
Ligands:, , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CLPS_ECOLI Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1r6o, resolution 2.25Å

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