1r1r: Difference between revisions

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-{{Seed}}
-[[Image:1r1r.png|left|200px]]
-<!--
+==RIBONUCLEOTIDE REDUCTASE R1 PROTEIN MUTANT Y730F WITH A REDUCED ACTIVE SITE FROM ESCHERICHIA COLI==
-The line below this paragraph, containing "STRUCTURE_1r1r", creates the "Structure Box" on the page.
+<StructureSection load='1r1r' size='340' side='right'caption='[[1r1r]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1r1r]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R1R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R1R FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r1r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r1r OCA], [https://pdbe.org/1r1r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r1r RCSB], [https://www.ebi.ac.uk/pdbsum/1r1r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r1r ProSAT]</span></td></tr>
-{{STRUCTURE_1r1r|  PDB=1r1r  |  SCENE=  }}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/RIR1_ECOLI RIR1_ECOLI] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1 contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide. It also provides redox-active cysteines.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r1/1r1r_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r1r ConSurf].
+<div style="clear:both"></div>
-===RIBONUCLEOTIDE REDUCTASE R1 PROTEIN MUTANT Y730F WITH A REDUCED ACTIVE SITE FROM ESCHERICHIA COLI===
+==See Also==
+*[[Ribonucleotide reductase 3D structures|Ribonucleotide reductase 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_9309223}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 9309223 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_9309223}}
-==About this Structure==
-R1R is a 7 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R1R OCA].
-==Reference==
-<ref group="xtra">PMID:9309223</ref><references group="xtra"/>
 [[Category: Escherichia coli]]
-[[Category: Ribonucleoside-diphosphate reductase]]
+[[Category: Large Structures]]
-[[Category: Eklund, H.]]
+[[Category: Eklund H]]
-[[Category: Eriksson, M.]]
+[[Category: Eriksson M]]
-[[Category: Deoxyribonucleotide synthesis]]
-[[Category: Oxidoreductase]]
-[[Category: Radical chemistry]]
-[[Category: Redox center]]
-[[Category: Ribonucleotide reductase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 10:01:58 2009''