1qzh: Difference between revisions

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[[Image:1qzh.png|left|200px]]


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==Crystal structure of Pot1 (protection of telomere)- ssDNA complex==
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<StructureSection load='1qzh' size='340' side='right'caption='[[1qzh]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1qzh]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QZH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QZH FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qzh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qzh OCA], [https://pdbe.org/1qzh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qzh RCSB], [https://www.ebi.ac.uk/pdbsum/1qzh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qzh ProSAT]</span></td></tr>
{{STRUCTURE_1qzh|  PDB=1qzh  |  SCENE=  }}
</table>
 
== Function ==
===Crystal structure of Pot1 (protection of telomere)- ssDNA complex===
[https://www.uniprot.org/uniprot/POT1_SCHPO POT1_SCHPO] Single-stranded telomeric DNA-binding protein that is required to protect the 3'-end telomeric overhang. It binds the consensus sequence 5'-GGTTAC-3'. Regulates telomerase and telomere length.<ref>PMID:11349150</ref> <ref>PMID:12463756</ref> <ref>PMID:18535244</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qz/1qzh_consurf.spt"</scriptWhenChecked>
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==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qzh ConSurf].
1QZH is a 12 chains structure of sequences from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QZH OCA].  
<div style="clear:both"></div>
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:14614509</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Schizosaccharomyces pombe]]
[[Category: Schizosaccharomyces pombe]]
[[Category: Baumann, P.]]
[[Category: Baumann P]]
[[Category: Cech, T R.]]
[[Category: Cech TR]]
[[Category: Lei, M.]]
[[Category: Lei M]]
[[Category: Podell, E R.]]
[[Category: Podell ER]]
[[Category: Protein-dna complex]]
[[Category: Single-stranded telomeric dna]]
 
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