1qzc: Difference between revisions

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-[[Image:1qzc.png|left|200px]]
-{{STRUCTURE_1qzc|  PDB=1qzc  |  SCENE=  }}
+==Coordinates of S12, SH44, LH69 and SRL separately fitted into the cryo-EM map of EF-Tu ternary complex (GDP.Kirromycin) bound 70S ribosome==
+<SX load='1qzc' size='340' side='right' viewer='molstar' caption='[[1qzc]], [[Resolution|resolution]] 9.00&Aring;' scene=''>
-===Coordinates of S12, SH44, LH69 and SRL separately fitted into the cryo-EM map of EF-Tu ternary complex (GDP.Kirromycin) bound 70S ribosome===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1qzc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QZC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QZC FirstGlance]. <br>
-{{ABSTRACT_PUBMED_14566331}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 9&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qzc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qzc OCA], [https://pdbe.org/1qzc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qzc RCSB], [https://www.ebi.ac.uk/pdbsum/1qzc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qzc ProSAT]</span></td></tr>
-==About this Structure==
+</table>
-[[1qzc]] is a 4 chain structure of [[Ribosomal protein S12]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QZC OCA].
+== Function ==
+[https://www.uniprot.org/uniprot/RS12_THET8 RS12_THET8] With S4 and S5 plays an important role in translational accuracy (By similarity).[HAMAP-Rule:MF_00403_B]  Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.[HAMAP-Rule:MF_00403_B]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qz/1qzc_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qzc ConSurf].
+<div style="clear:both"></div>
 ==See Also==
 *[[Ribosomal protein S12|Ribosomal protein S12]]
+__TOC__
-==Reference==
+</SX>
-<ref group="xtra">PMID:014566331</ref><references group="xtra"/>
 [[Category: Escherichia coli]]
+[[Category: Large Structures]]
 [[Category: Thermus thermophilus]]
-[[Category: Ehrenberg, M.]]
+[[Category: Ehrenberg M]]
-[[Category: Frank, J.]]
+[[Category: Frank J]]
-[[Category: Harvey, S C.]]
+[[Category: Harvey SC]]
-[[Category: Li, W.]]
+[[Category: Li W]]
-[[Category: Nielsen, R C.]]
+[[Category: Nielsen RC]]
-[[Category: Nissen, P.]]
+[[Category: Nissen P]]
-[[Category: Sengupta, J.]]
+[[Category: Sengupta J]]
-[[Category: Stagg, S M.]]
+[[Category: Stagg SM]]
-[[Category: Valle, M.]]
+[[Category: Valle M]]
-[[Category: Zavialov, A.]]
+[[Category: Zavialov A]]
-[[Category: Ribosomal protein]]
-[[Category: Rna binding protein-rna complex]]
-[[Category: Rrna]]