1qr7: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
m Protected "1qr7" [edit=sysop:move=sysop]
No edit summary
 
(8 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:1qr7.png|left|200px]]


{{STRUCTURE_1qr7|  PDB=1qr7  |  SCENE=  }}
==CRYSTAL STRUCTURE OF PHENYLALANINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM ESCHERICHIA COLI COMPLEXED WITH PB2+ AND PEP==
 
<StructureSection load='1qr7' size='340' side='right'caption='[[1qr7]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
===CRYSTAL STRUCTURE OF PHENYLALANINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM ESCHERICHIA COLI COMPLEXED WITH PB2+ AND PEP===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1qr7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QR7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QR7 FirstGlance]. <br>
{{ABSTRACT_PUBMED_10425687}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PB:LEAD+(II)+ION'>PB</scene>, <scene name='pdbligand=PEP:PHOSPHOENOLPYRUVATE'>PEP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qr7 OCA], [https://pdbe.org/1qr7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qr7 RCSB], [https://www.ebi.ac.uk/pdbsum/1qr7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qr7 ProSAT]</span></td></tr>
[[1qr7]] is a 4 chain structure of [[Aldolase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QR7 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/AROG_ECOLI AROG_ECOLI] Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qr/1qr7_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qr7 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Aldolase|Aldolase]]
*[[DAHP synthase 3D structures|DAHP synthase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:010425687</ref><references group="xtra"/>
[[Category: 3-deoxy-7-phosphoheptulonate synthase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Bauerle, R H.]]
[[Category: Large Structures]]
[[Category: Kretsinger, R H.]]
[[Category: Bauerle RH]]
[[Category: Shumilin, I A.]]
[[Category: Kretsinger RH]]
[[Category: Beta-alpha-barrel]]
[[Category: Shumilin IA]]
[[Category: Lyase]]

Latest revision as of 11:16, 14 February 2024

CRYSTAL STRUCTURE OF PHENYLALANINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM ESCHERICHIA COLI COMPLEXED WITH PB2+ AND PEPCRYSTAL STRUCTURE OF PHENYLALANINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM ESCHERICHIA COLI COMPLEXED WITH PB2+ AND PEP

Structural highlights

1qr7 is a 4 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.6Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

AROG_ECOLI Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1qr7, resolution 2.60Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA