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| {{STRUCTURE_1qcr| PDB=1qcr | SCENE= }}
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| ===CRYSTAL STRUCTURE OF BOVINE MITOCHONDRIAL CYTOCHROME BC1 COMPLEX, ALPHA CARBON ATOMS ONLY===
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| {{ABSTRACT_PUBMED_9204897}}
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| ==Function== | | ==CRYSTAL STRUCTURE OF BOVINE MITOCHONDRIAL CYTOCHROME BC1 COMPLEX, ALPHA CARBON ATOMS ONLY== |
| [[http://www.uniprot.org/uniprot/QCR10_BOVIN QCR10_BOVIN]] This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may be closely linked to the iron-sulfur protein in the complex and function as an iron-sulfur protein binding factor. [[http://www.uniprot.org/uniprot/CYB_BOVIN CYB_BOVIN]] Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. [[http://www.uniprot.org/uniprot/UCRI_BOVIN UCRI_BOVIN]] Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. The transit peptide of the Rieske protein seems to form part of the bc1 complex and is considered to be the subunit 11/IX of that complex. [[http://www.uniprot.org/uniprot/QCR2_BOVIN QCR2_BOVIN]] This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex. [[http://www.uniprot.org/uniprot/QCR6_BOVIN QCR6_BOVIN]] This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. [[http://www.uniprot.org/uniprot/QCR1_BOVIN QCR1_BOVIN]] This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. [[http://www.uniprot.org/uniprot/CY1_BOVIN CY1_BOVIN]] This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain. [[http://www.uniprot.org/uniprot/QCR9_BOVIN QCR9_BOVIN]] This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit interacts with cytochrome c1. | | <StructureSection load='1qcr' size='340' side='right'caption='[[1qcr]], [[Resolution|resolution]] 2.70Å' scene=''> |
| | | == Structural highlights == |
| ==About this Structure==
| | <table><tr><td colspan='2'>[[1qcr]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QCR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QCR FirstGlance]. <br> |
| [[1qcr]] is a 11 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QCR OCA].
| | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> |
| | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> |
| | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qcr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qcr OCA], [https://pdbe.org/1qcr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qcr RCSB], [https://www.ebi.ac.uk/pdbsum/1qcr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qcr ProSAT]</span></td></tr> |
| | </table> |
| | == Function == |
| | [https://www.uniprot.org/uniprot/QCR1_BOVIN QCR1_BOVIN] This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. |
| | == Evolutionary Conservation == |
| | [[Image:Consurf_key_small.gif|200px|right]] |
| | Check<jmol> |
| | <jmolCheckbox> |
| | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qc/1qcr_consurf.spt"</scriptWhenChecked> |
| | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| | <text>to colour the structure by Evolutionary Conservation</text> |
| | </jmolCheckbox> |
| | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qcr ConSurf]. |
| | <div style="clear:both"></div> |
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| ==See Also== | | ==See Also== |
| *[[Cytochrome bc1 complex|Cytochrome bc1 complex]] | | *[[Cytochrome C 3D structures|Cytochrome C 3D structures]] |
| *[[Cytochrome c|Cytochrome c]] | | *[[Cytochrome bc1 3D structures|Cytochrome bc1 3D structures]] |
| | | __TOC__ |
| ==Reference==
| | </StructureSection> |
| <ref group="xtra">PMID:009204897</ref><references group="xtra"/><references/>
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| [[Category: Bos taurus]] | | [[Category: Bos taurus]] |
| [[Category: Ubiquinol--cytochrome-c reductase]] | | [[Category: Large Structures]] |
| [[Category: Deisenhofer, J.]] | | [[Category: Deisenhofer J]] |
| [[Category: Kachurin, A.]] | | [[Category: Kachurin A]] |
| [[Category: Kim, H.]] | | [[Category: Kim H]] |
| [[Category: Xia, D.]] | | [[Category: Xia D]] |
| [[Category: Xia, J Z.]] | | [[Category: Xia JZ]] |
| [[Category: Yu, C A.]] | | [[Category: Yu CA]] |
| [[Category: Yu, L.]] | | [[Category: Yu L]] |
| [[Category: Zhang, L.]] | | [[Category: Zhang L]] |
| [[Category: Bc1]]
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| [[Category: Cytochrome b]]
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| [[Category: Cytochrome c1]]
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| [[Category: Electron transfer]]
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| [[Category: Iron sulfer protein]]
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| [[Category: Membrane protein]]
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| [[Category: Mitochondrial processing peptidase]]
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| [[Category: Mpp]]
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| [[Category: Oxidoreductase]]
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| [[Category: Protease]]
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| [[Category: Proton translocation]]
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| [[Category: Qcr]]
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| [[Category: Rieske]]
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