1q13: Difference between revisions

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-[[Image:1q13.png|left|200px]]
-{{STRUCTURE_1q13|  PDB=1q13  |  SCENE=  }}
+==Crystal structure of rabbit 20alpha hyroxysteroid dehydrogenase in ternary complex with NADP and testosterone==
+<StructureSection load='1q13' size='340' side='right'caption='[[1q13]], [[Resolution|resolution]] 2.08&Aring;' scene=''>
-===Crystal structure of rabbit 20alpha hyroxysteroid dehydrogenase in ternary complex with NADP and testosterone===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1q13]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q13 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Q13 FirstGlance]. <br>
-{{ABSTRACT_PUBMED_15123423}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.08&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TES:TESTOSTERONE'>TES</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1q13 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q13 OCA], [https://pdbe.org/1q13 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1q13 RCSB], [https://www.ebi.ac.uk/pdbsum/1q13 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q13 ProSAT]</span></td></tr>
-[[1q13]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q13 OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PE2R_RABIT PE2R_RABIT] Can convert prostaglandin E2 to prostaglandin F2-alpha.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q1/1q13_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1q13 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Hydroxysteroid dehydrogenase|Hydroxysteroid dehydrogenase]]
+*[[Hydroxysteroid dehydrogenase 3D structures|Hydroxysteroid dehydrogenase 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:015123423</ref><references group="xtra"/>
+[[Category: Large Structures]]
 [[Category: Oryctolagus cuniculus]]
-[[Category: Breton, R.]]
+[[Category: Breton R]]
-[[Category: Cantin, L.]]
+[[Category: Cantin L]]
-[[Category: Couture, J F.]]
+[[Category: Couture J-F]]
-[[Category: Labrie, F.]]
+[[Category: Labrie F]]
-[[Category: Legrand, P.]]
+[[Category: Legrand P]]
-[[Category: Luu-The, V.]]
+[[Category: Luu-The V]]
-[[Category: 20alpha-hsd]]
-[[Category: Akr]]
-[[Category: Aldo-keto reductase]]
-[[Category: Hydroxysteroid dehydrogenase]]
-[[Category: Oxidoreductase]]
-[[Category: Ternary complex]]
-[[Category: Testosterone]]
-[[Category: Tim-barrel]]