1pqc: Difference between revisions

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-{{Seed}}
-[[Image:1pqc.png|left|200px]]
-<!--
+==HUMAN LXR BETA HORMONE RECEPTOR COMPLEXED WITH T0901317==
-The line below this paragraph, containing "STRUCTURE_1pqc", creates the "Structure Box" on the page.
+<StructureSection load='1pqc' size='340' side='right'caption='[[1pqc]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1pqc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PQC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PQC FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=444:N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE'>444</scene></td></tr>
-{{STRUCTURE_1pqc|  PDB=1pqc  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pqc OCA], [https://pdbe.org/1pqc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pqc RCSB], [https://www.ebi.ac.uk/pdbsum/1pqc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pqc ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/NR1H2_HUMAN NR1H2_HUMAN] Orphan receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8 (By similarity).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pq/1pqc_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pqc ConSurf].
+<div style="clear:both"></div>
-===HUMAN LXR BETA HORMONE RECEPTOR COMPLEXED WITH T0901317===
+==See Also==
+*[[Liver X receptor|Liver X receptor]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_12819202}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 12819202 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_12819202}}
-==About this Structure==
-PQC is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PQC OCA].
-==Reference==
-<ref group="xtra">PMID:12819202</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: Ahola, H.]]
+[[Category: Large Structures]]
-[[Category: Bonn, T.]]
+[[Category: Ahola H]]
-[[Category: Carlquist, M.]]
+[[Category: Bonn T]]
-[[Category: Farnegardh, M.]]
+[[Category: Carlquist M]]
-[[Category: Gustafsson, J A.]]
+[[Category: Farnegardh M]]
-[[Category: Ljunggren, J.]]
+[[Category: Gustafsson J-A]]
-[[Category: Sun, S.]]
+[[Category: Ljunggren J]]
-[[Category: Wilhelmsson, A.]]
+[[Category: Sun S]]
-[[Category: Lxrb+t0901317]]
+[[Category: Wilhelmsson A]]
-[[Category: Transcription regulation]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr  2 16:17:41 2009''