1pl5: Difference between revisions

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[[Image:1pl5.png|left|200px]]


{{STRUCTURE_1pl5|  PDB=1pl5  |  SCENE=  }}
==Crystal Structure Analysis of the Sir4p C-terminal Coiled Coil==
 
<StructureSection load='1pl5' size='340' side='right'caption='[[1pl5]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
===Crystal Structure Analysis of the Sir4p C-terminal Coiled Coil===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1pl5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PL5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PL5 FirstGlance]. <br>
{{ABSTRACT_PUBMED_14636601}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pl5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pl5 OCA], [https://pdbe.org/1pl5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pl5 RCSB], [https://www.ebi.ac.uk/pdbsum/1pl5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pl5 ProSAT]</span></td></tr>
==About this Structure==
</table>
[[1pl5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PL5 OCA].  
== Function ==
[https://www.uniprot.org/uniprot/SIR4_YEAST SIR4_YEAST] The proteins SIR1 through SIR4 are required for transcriptional repression of the silent mating type loci, HML and HMR. The proteins SIR2 through SIR4 repress mulitple loci by modulating chromatin structure. Involves the compaction of chromatin fiber into a more condensed form.<ref>PMID:18039933</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Chen, L.]]
[[Category: Chen L]]
[[Category: Murphy, G A.]]
[[Category: Murphy GA]]
[[Category: Pillus, L.]]
[[Category: Pillus L]]
[[Category: Powell, S T.]]
[[Category: Powell ST]]
[[Category: Schultz, S C.]]
[[Category: Schultz SC]]
[[Category: Spedale, E J.]]
[[Category: Spedale EJ]]
[[Category: Dna binding protein-transcription complex]]
[[Category: Parallel coiled coil homodimer]]

Latest revision as of 11:08, 14 February 2024

Crystal Structure Analysis of the Sir4p C-terminal Coiled CoilCrystal Structure Analysis of the Sir4p C-terminal Coiled Coil

Structural highlights

1pl5 is a 2 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.5Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SIR4_YEAST The proteins SIR1 through SIR4 are required for transcriptional repression of the silent mating type loci, HML and HMR. The proteins SIR2 through SIR4 repress mulitple loci by modulating chromatin structure. Involves the compaction of chromatin fiber into a more condensed form.[1]

References

  1. ↑ Bupp JM, Martin AE, Stensrud ES, Jaspersen SL. Telomere anchoring at the nuclear periphery requires the budding yeast Sad1-UNC-84 domain protein Mps3. J Cell Biol. 2007 Dec 3;179(5):845-54. Epub 2007 Nov 26. PMID:18039933 doi:http://dx.doi.org/10.1083/jcb.200706040

1pl5, resolution 2.50Å

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OCA
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