1ph6: Difference between revisions

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[[Image:1ph6.png|left|200px]]


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==Crystal Structure of THE OXYTRICHA NOVA TELOMERE END-BINDING PROTEIN COMPLEXED WITH NONCOGNATE SSDNA GGGGTTTTGTGG==
The line below this paragraph, containing "STRUCTURE_1ph6", creates the "Structure Box" on the page.
<StructureSection load='1ph6' size='340' side='right'caption='[[1ph6]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1ph6]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Sterkiella_nova Sterkiella nova]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PH6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PH6 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
{{STRUCTURE_1ph6| PDB=1ph6 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ph6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ph6 OCA], [https://pdbe.org/1ph6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ph6 RCSB], [https://www.ebi.ac.uk/pdbsum/1ph6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ph6 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TEBA_STENO TEBA_STENO] May function as protective capping of the single-stranded telomeric overhang. May also participate in telomere length regulation during DNA replication. Binds specifically to the T4G4-containing extension on the 3'strand and protects this region of the telomere from nuclease digestion and chemical modification.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ph/1ph6_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ph6 ConSurf].
<div style="clear:both"></div>


===Crystal Structure of THE OXYTRICHA NOVA TELOMERE END-BINDING PROTEIN COMPLEXED WITH NONCOGNATE SSDNA GGGGTTTTGTGG===
==See Also==
 
*[[End-binding protein|End-binding protein]]
 
__TOC__
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_12912928}}
 
==About this Structure==
1PH6 is a 5 chains structure of sequences from [http://en.wikipedia.org/wiki/Sterkiella_nova Sterkiella nova]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PH6 OCA].
 
==Reference==
<ref group="xtra">PMID:12912928</ref><references group="xtra"/>
[[Category: Sterkiella nova]]
[[Category: Sterkiella nova]]
[[Category: Schultz, S C.]]
[[Category: Schultz SC]]
[[Category: Theobald, D L.]]
[[Category: Theobald DL]]
[[Category: Noncognate]]
[[Category: Ob fold]]
[[Category: Oligonucleotide and oligosaccharide binding fold]]
[[Category: Protein dna interaction]]
[[Category: Protein/dna]]
[[Category: Sequence specificity]]
[[Category: Single strand dna binding protein]]
[[Category: Telomere]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 23:57:32 2009''

Latest revision as of 11:08, 14 February 2024

Crystal Structure of THE OXYTRICHA NOVA TELOMERE END-BINDING PROTEIN COMPLEXED WITH NONCOGNATE SSDNA GGGGTTTTGTGGCrystal Structure of THE OXYTRICHA NOVA TELOMERE END-BINDING PROTEIN COMPLEXED WITH NONCOGNATE SSDNA GGGGTTTTGTGG

Structural highlights

1ph6 is a 5 chain structure with sequence from Sterkiella nova. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.1Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TEBA_STENO May function as protective capping of the single-stranded telomeric overhang. May also participate in telomere length regulation during DNA replication. Binds specifically to the T4G4-containing extension on the 3'strand and protects this region of the telomere from nuclease digestion and chemical modification.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1ph6, resolution 2.10Å

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