1pgx: Difference between revisions

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[[Image:1pgx.png|left|200px]]


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==THE 1.66 ANGSTROMS X-RAY STRUCTURE OF THE B2 IMMUNOGLOBULIN-BINDING DOMAIN OF STREPTOCOCCAL PROTEIN G AND COMPARISON TO THE NMR STRUCTURE OF THE B1 DOMAIN==
The line below this paragraph, containing "STRUCTURE_1pgx", creates the "Structure Box" on the page.
<StructureSection load='1pgx' size='340' side='right'caption='[[1pgx]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1pgx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus Streptococcus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PGX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PGX FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.66&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pgx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pgx OCA], [https://pdbe.org/1pgx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pgx RCSB], [https://www.ebi.ac.uk/pdbsum/1pgx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pgx ProSAT]</span></td></tr>
{{STRUCTURE_1pgx| PDB=1pgx |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/SPG1_STRSG SPG1_STRSG] Binds to the constant Fc region of IgG with high affinity.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pg/1pgx_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pgx ConSurf].
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===THE 1.66 ANGSTROMS X-RAY STRUCTURE OF THE B2 IMMUNOGLOBULIN-BINDING DOMAIN OF STREPTOCOCCAL PROTEIN G AND COMPARISON TO THE NMR STRUCTURE OF THE B1 DOMAIN===
==See Also==
 
*[[Protein G|Protein G]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_1420164}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 1420164 is the PubMed ID number.
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{{ABSTRACT_PUBMED_1420164}}
 
==About this Structure==
1PGX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus Streptococcus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PGX OCA].
 
==Reference==
1.67-A X-ray structure of the B2 immunoglobulin-binding domain of streptococcal protein G and comparison to the NMR structure of the B1 domain., Achari A, Hale SP, Howard AJ, Clore GM, Gronenborn AM, Hardman KD, Whitlow M, Biochemistry. 1992 Nov 3;31(43):10449-57. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1420164 1420164]
[[Category: Single protein]]
[[Category: Streptococcus]]
[[Category: Streptococcus]]
[[Category: Achari, A.]]
[[Category: Achari A]]
[[Category: Howard, A J.]]
[[Category: Howard AJ]]
[[Category: Whitlow, M.]]
[[Category: Whitlow M]]
[[Category: Immunoglobulin binding protein]]
 
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