1pe7: Difference between revisions

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[[Image:1pe7.jpg|left|200px]]<br /><applet load="1pe7" size="350" color="white" frame="true" align="right" spinBox="true"
caption="1pe7, resolution 1.82&Aring;" />
'''Thermolysin with bicyclic inhibitor'''<br />


==About this Structure==
==Thermolysin with bicyclic inhibitor==
1PE7 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=4BR:'>4BR</scene>, <scene name='pdbligand=LEU:'>LEU</scene> and <scene name='pdbligand=DMS:'>DMS</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PE7 OCA].  
<StructureSection load='1pe7' size='340' side='right'caption='[[1pe7]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1pe7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PE7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PE7 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4BR:2-(4-METHYLPHENOXY)ETHYLPHOSPHINATE'>4BR</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=LEN:3-METHYLBUTAN-1-AMINE'>LEN</scene>, <scene name='pdbligand=LEU:LEUCINE'>LEU</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pe7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pe7 OCA], [https://pdbe.org/1pe7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pe7 RCSB], [https://www.ebi.ac.uk/pdbsum/1pe7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pe7 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/THER_BACTH THER_BACTH] Extracellular zinc metalloprotease.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pe/1pe7_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pe7 ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Thermolysin 3D structures|Thermolysin 3D structures]]
__TOC__
</StructureSection>
[[Category: Bacillus thermoproteolyticus]]
[[Category: Bacillus thermoproteolyticus]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Thermolysin]]
[[Category: Bartlett PA]]
[[Category: Bartlett, P A.]]
[[Category: Juers D]]
[[Category: Juers, D.]]
[[Category: Matthews BW]]
[[Category: Matthews, B W.]]
[[Category: Yusuff N]]
[[Category: Yusuff, N.]]
[[Category: 4BR]]
[[Category: CA]]
[[Category: DMS]]
[[Category: LEU]]
[[Category: ZN]]
[[Category: hydrolase]]
[[Category: metalloprotease]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:27:52 2008''

Latest revision as of 11:07, 14 February 2024

Thermolysin with bicyclic inhibitorThermolysin with bicyclic inhibitor

Structural highlights

1pe7 is a 1 chain structure with sequence from Bacillus thermoproteolyticus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.82Å
Ligands:, , , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

THER_BACTH Extracellular zinc metalloprotease.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1pe7, resolution 1.82Å

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