1pdl: Difference between revisions

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-[[Image:1pdl.png|left|200px]]
-{{STRUCTURE_1pdl|  PDB=1pdl  |  SCENE=  }}
+==Fitting of gp5 in the cryoEM reconstruction of the bacteriophage T4 baseplate==
+<SX load='1pdl' size='340' side='right' viewer='molstar' caption='[[1pdl]], [[Resolution|resolution]] 12.00&Aring;' scene=''>
-===Fitting of gp5 in the cryoEM reconstruction of the bacteriophage T4 baseplate===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1pdl]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PDL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PDL FirstGlance]. <br>
-{{ABSTRACT_PUBMED_12923574}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 12&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pdl OCA], [https://pdbe.org/1pdl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pdl RCSB], [https://www.ebi.ac.uk/pdbsum/1pdl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pdl ProSAT]</span></td></tr>
-==About this Structure==
+</table>
-[[1pdl]] is a 3 chain structure of [[Hen Egg-White (HEW) Lysozyme]] with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PDL OCA].
+== Function ==
+[https://www.uniprot.org/uniprot/NEEDL_BPT4 NEEDL_BPT4] Tail-associated lysozyme of the baseplate hub that is essential for localized hydrolysis of bacterial cell wall necessary for viral DNA injection. The needle-like gp5 protein punctures the outer cell membrane and then digests the peptidoglycan cell wall in the periplasmic space. Involved in the tail assembly.<ref>PMID:12837775</ref> <ref>PMID:21129200</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pd/1pdl_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pdl ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Hen Egg-White (HEW) Lysozyme|Hen Egg-White (HEW) Lysozyme]]
+*[[Lysozyme 3D structures|Lysozyme 3D structures]]
+== References ==
-==Reference==
+<references/>
-<ref group="xtra">PMID:012923574</ref><references group="xtra"/>
+__TOC__
-[[Category: Enterobacteria phage t4]]
+</SX>
-[[Category: Lysozyme]]
+[[Category: Escherichia virus T4]]
-[[Category: Arisaka, F.]]
+[[Category: Large Structures]]
-[[Category: Chipman, P R.]]
+[[Category: Arisaka F]]
-[[Category: Kanamaru, S.]]
+[[Category: Chipman PR]]
-[[Category: Kostyuchenko, V A.]]
+[[Category: Kanamaru S]]
-[[Category: Leiman, P G.]]
+[[Category: Kostyuchenko VA]]
-[[Category: Mesyanzhinov, V V.]]
+[[Category: Leiman PG]]
-[[Category: Raaij, M J.van.]]
+[[Category: Mesyanzhinov VV]]
-[[Category: Rossmann, M G.]]
+[[Category: Rossmann MG]]
-[[Category: Hydrolase]]
+[[Category: Van Raaij MJ]]