1pdf: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-[[Image:1pdf.gif|left|200px]]<br /><applet load="1pdf" size="450" color="white" frame="true" align="right" spinBox="true"
-caption="1pdf" />
-'''Fitting of gp11 crystal structure into 3D cryo-EM reconstruction of bacteriophage T4 baseplate-tail tube complex'''<br />
-==Overview==
+==Fitting of gp11 crystal structure into 3D cryo-EM reconstruction of bacteriophage T4 baseplate-tail tube complex==
-The baseplate of bacteriophage T4 is a multiprotein molecular machine that, controls host cell recognition, attachment, tail sheath contraction and, viral DNA ejection. We report here the three-dimensional structure of the, baseplate-tail tube complex determined to a resolution of 12 A by, cryoelectron microscopy. The baseplate has a six-fold symmetric, dome-like, structure approximately 520 A in diameter and approximately 270 A long, assembled around a central hub. A 940 A-long and 96 A-diameter tail tube, coaxial with the hub, is connected to the top of the baseplate. At the, center of the dome is a needle-like structure that was previously, identified as a cell puncturing device. We have identified the locations, of six proteins with known atomic structures, and established the position, and shape of several other baseplate proteins. The baseplate structure, suggests a mechanism of baseplate triggering and structural transition, during the initial stages of T4 infection.
+<SX load='1pdf' size='340' side='right' viewer='molstar' caption='[[1pdf]], [[Resolution|resolution]] 12.00&Aring;' scene=''>
+== Structural highlights ==
-==About this Structure==
+<table><tr><td colspan='2'>[[1pdf]] is a 18 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PDF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PDF FirstGlance]. <br>
-PDF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacteriophage_t4 Bacteriophage t4]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1PDF OCA].
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 12&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pdf OCA], [https://pdbe.org/1pdf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pdf RCSB], [https://www.ebi.ac.uk/pdbsum/1pdf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pdf ProSAT]</span></td></tr>
-==Reference==
+</table>
-Three-dimensional structure of bacteriophage T4 baseplate., Kostyuchenko VA, Leiman PG, Chipman PR, Kanamaru S, van Raaij MJ, Arisaka F, Mesyanzhinov VV, Rossmann MG, Nat Struct Biol. 2003 Sep;10(9):688-93. Epub 2003 Aug 17. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12923574 12923574]
+== Function ==
-[[Category: Bacteriophage t4]]
+[https://www.uniprot.org/uniprot/BP11_BPT4 BP11_BPT4] Baseplate protein that is part of the baseplate wedge and that connects the short tail fibers to the baseplate (PubMed:15315755). Involved in the tail assembly.<ref>PMID:15315755</ref> <ref>PMID:21129200</ref>
-[[Category: Single protein]]
+== Evolutionary Conservation ==
-[[Category: Arisaka, F.]]
+[[Image:Consurf_key_small.gif|200px|right]]
-[[Category: Chipman, P.R.]]
+Check<jmol>
-[[Category: Kanamaru, S.]]
+  <jmolCheckbox>
-[[Category: Kostyuchenko, V.A.]]
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pd/1pdf_consurf.spt"</scriptWhenChecked>
-[[Category: Leiman, P.G.]]
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-[[Category: Mesyanzhinov, V.V.]]
+    <text>to colour the structure by Evolutionary Conservation</text>
-[[Category: Raaij, M.J.van.]]
+  </jmolCheckbox>
-[[Category: Rossmann, M.G.]]
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pdf ConSurf].
-[[Category: structural protein]]
+<div style="clear:both"></div>
+== References ==
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 23:42:32 2007''
+<references/>
+__TOC__
+</SX>
+[[Category: Escherichia virus T4]]
+[[Category: Large Structures]]
+[[Category: Arisaka F]]
+[[Category: Chipman PR]]
+[[Category: Kanamaru S]]
+[[Category: Kostyuchenko VA]]
+[[Category: Leiman PG]]
+[[Category: Mesyanzhinov VV]]
+[[Category: Rossmann MG]]
+[[Category: Van Raaij MJ]]