1nrj: Difference between revisions

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-[[Image:1nrj.png|left|200px]]
-{{STRUCTURE_1nrj|  PDB=1nrj  |  SCENE=  }}
+==Signal Recognition Particle Receptor Beta-Subunit in Complex with the SRX Domain from the Alpha-Subunit==
+<StructureSection load='1nrj' size='340' side='right'caption='[[1nrj]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
-===Signal Recognition Particle Receptor Beta-Subunit in Complex with the SRX Domain from the Alpha-Subunit===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1nrj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NRJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NRJ FirstGlance]. <br>
-{{ABSTRACT_PUBMED_12654246}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nrj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nrj OCA], [https://pdbe.org/1nrj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nrj RCSB], [https://www.ebi.ac.uk/pdbsum/1nrj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nrj ProSAT]</span></td></tr>
-[[1nrj]] is a 2 chain structure of [[Signal recognition particle receptor]] with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NRJ OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/SRPR_YEAST SRPR_YEAST] Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. GTP hydrolysis may enhance the fidelity of and provide unidirectionality to the targeting reaction. It is important but not essential for cell growth. May be directly involved in mitochondrial protein import.<ref>PMID:1327299</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nr/1nrj_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nrj ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Signal recognition particle receptor|Signal recognition particle receptor]]
+*[[Signal recognition particle receptor 3D structures|Signal recognition particle receptor 3D structures]]
+== References ==
-==Reference==
+<references/>
-<ref group="xtra">PMID:012654246</ref><references group="xtra"/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Saccharomyces cerevisiae]]
-[[Category: Schwartz, T.]]
+[[Category: Schwartz T]]
-[[Category: Endoplasmic reticulum]]
-[[Category: Gtp-binding]]
-[[Category: Gtpase-effector complex]]
-[[Category: Protein transport]]
-[[Category: Receptor]]
-[[Category: Signal recognition particle]]
-[[Category: Transmembrane]]