1nqm: Difference between revisions

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{{Seed}}
[[Image:1nqm.png|left|200px]]


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==Structure of Savm-W120K, streptavidin mutant==
The line below this paragraph, containing "STRUCTURE_1nqm", creates the "Structure Box" on the page.
<StructureSection load='1nqm' size='340' side='right'caption='[[1nqm]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1nqm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NQM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NQM FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTN:BIOTIN'>BTN</scene></td></tr>
{{STRUCTURE_1nqm| PDB=1nqm |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nqm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nqm OCA], [https://pdbe.org/1nqm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nqm RCSB], [https://www.ebi.ac.uk/pdbsum/1nqm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nqm ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nq/1nqm_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nqm ConSurf].
<div style="clear:both"></div>


===Structure of Savm-W120K, streptavidin mutant===
==See Also==
 
*[[Avidin 3D structures|Avidin 3D structures]]
 
__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_12837778}}
 
==About this Structure==
1NQM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NQM OCA].
 
==Reference==
Dimer-tetramer transition between solution and crystalline states of streptavidin and avidin mutants., Pazy Y, Eisenberg-Domovich Y, Laitinen OH, Kulomaa MS, Bayer EA, Wilchek M, Livnah O, J Bacteriol. 2003 Jul;185(14):4050-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12837778 12837778]
[[Category: Single protein]]
[[Category: Streptomyces avidinii]]
[[Category: Streptomyces avidinii]]
[[Category: Bayer, E A.]]
[[Category: Bayer EA]]
[[Category: Eisenberg-Domovich, Y.]]
[[Category: Eisenberg-Domovich Y]]
[[Category: Kulomaa, M S.]]
[[Category: Kulomaa MS]]
[[Category: Laitinen, O H.]]
[[Category: Laitinen OH]]
[[Category: Livnah, O.]]
[[Category: Livnah O]]
[[Category: Pazy, Y.]]
[[Category: Pazy Y]]
[[Category: Wilchek, M.]]
[[Category: Wilchek M]]
[[Category: Avidin]]
[[Category: Biotin]]
[[Category: High affinity system]]
[[Category: Monomer-monomer interaction]]
[[Category: Streptavidin]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 14:22:07 2008''

Latest revision as of 10:58, 14 February 2024

Structure of Savm-W120K, streptavidin mutantStructure of Savm-W120K, streptavidin mutant

Structural highlights

1nqm is a 4 chain structure with sequence from Streptomyces avidinii. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.7Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SAV_STRAV The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1nqm, resolution 1.70Å

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