1nl3: Difference between revisions
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==CRYSTAL STRUCTURE OF THE SECA PROTEIN TRANSLOCATION ATPASE FROM MYCOBACTERIUM TUBERCULOSIS in APO FORM== | |||
<StructureSection load='1nl3' size='340' side='right'caption='[[1nl3]], [[Resolution|resolution]] 2.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1nl3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NL3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NL3 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nl3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nl3 OCA], [https://pdbe.org/1nl3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nl3 RCSB], [https://www.ebi.ac.uk/pdbsum/1nl3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nl3 ProSAT], [https://www.topsan.org/Proteins/TBSGC/1nl3 TOPSAN]</span></td></tr> | |||
== | </table> | ||
[[1nl3]] is a 2 chain structure with sequence from [ | == Function == | ||
[https://www.uniprot.org/uniprot/SECA1_MYCTU SECA1_MYCTU] Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of precursor proteins, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane (By similarity). | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nl/1nl3_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nl3 ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | ==See Also== | ||
*[[Preprotein translocase 3D structures|Preprotein translocase 3D structures]] | |||
*[[SecA|SecA]] | *[[SecA|SecA]] | ||
__TOC__ | |||
</StructureSection> | |||
< | [[Category: Large Structures]] | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Arockiasamy | [[Category: Arockiasamy A]] | ||
[[Category: Braunstein | [[Category: Braunstein M]] | ||
[[Category: Holzenburg | [[Category: Holzenburg A]] | ||
[[Category: Jacobs | [[Category: Jacobs Jr WR]] | ||
[[Category: Ronning | [[Category: Ronning DR]] | ||
[[Category: Sacchettini | [[Category: Sacchettini JC]] | ||
[[Category: Savva | [[Category: Savva CG]] | ||
[[Category: Sharma | [[Category: Sharma V]] | ||