1ndl: Difference between revisions

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[[Image:1ndl.png|left|200px]]


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==THE AWD NUCLEOTIDE DIPHOSPHATE KINASE FROM DROSOPHILA==
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<StructureSection load='1ndl' size='340' side='right'caption='[[1ndl]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1ndl]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NDL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NDL FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ndl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ndl OCA], [https://pdbe.org/1ndl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ndl RCSB], [https://www.ebi.ac.uk/pdbsum/1ndl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ndl ProSAT]</span></td></tr>
{{STRUCTURE_1ndl| PDB=1ndl |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/NDKA_DROME NDKA_DROME] Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.<ref>PMID:2849580</ref> <ref>PMID:2175255</ref> <ref>PMID:7559441</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nd/1ndl_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ndl ConSurf].
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===THE AWD NUCLEOTIDE DIPHOSPHATE KINASE FROM DROSOPHILA===
==See Also==
 
*[[Nucleoside diphosphate kinase 3D structures|Nucleoside diphosphate kinase 3D structures]]
 
== References ==
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{{ABSTRACT_PUBMED_8081741}}
 
==About this Structure==
1NDL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NDL OCA].
 
==Reference==
Crystal structure of the Awd nucleotide diphosphate kinase from Drosophila., Chiadmi M, Morera S, Lascu I, Dumas C, Le Bras G, Veron M, Janin J, Structure. 1993 Dec 15;1(4):283-93. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8081741 8081741]
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
[[Category: Nucleoside-diphosphate kinase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Chiadmi M]]
[[Category: Chiadmi, M.]]
[[Category: Dumas C]]
[[Category: Dumas, C.]]
[[Category: Janin J]]
[[Category: Janin, J.]]
[[Category: Lascu I]]
[[Category: Lascu, I.]]
[[Category: Lebras G]]
[[Category: Lebras, G.]]
[[Category: Morera S]]
[[Category: Morera, S.]]
[[Category: Veron M]]
[[Category: Veron, M.]]
[[Category: Phosphotransferase]]
 
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