1nc5: Difference between revisions

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[[Image:1nc5.png|left|200px]]


{{STRUCTURE_1nc5|  PDB=1nc5  |  SCENE=  }}
==Structure of Protein of Unknown Function of YteR from Bacillus Subtilis==
 
<StructureSection load='1nc5' size='340' side='right'caption='[[1nc5]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
===Structure of Protein of Unknown Function of YteR from Bacillus Subtilis===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1nc5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NC5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NC5 FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nc5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nc5 OCA], [https://pdbe.org/1nc5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nc5 RCSB], [https://www.ebi.ac.uk/pdbsum/1nc5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nc5 ProSAT], [https://www.topsan.org/Proteins/MCSG/1nc5 TOPSAN]</span></td></tr>
[[1nc5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NC5 OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/URHG2_BACSU URHG2_BACSU] Catalyzes the hydrolysis of unsaturated rhamnogalacturonan disaccharide to yield unsaturated D-galacturonic acid and L-rhamnose. It cannot act on unsaturated glucuronyl hydrolase (UGL) substrates containing unsaturated D-glucuronic acid at the non-reducing terminus, although the active pockets of YesR and UGL are very similar.<ref>PMID:16781735</ref>  
<ref group="xtra">PMID:015906318</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nc/1nc5_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nc5 ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Collart, F.]]
[[Category: Large Structures]]
[[Category: Joachimiak, A.]]
[[Category: Collart F]]
[[Category: Korolev, S.]]
[[Category: Joachimiak A]]
[[Category: Lozondra, L.]]
[[Category: Korolev S]]
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Category: Lozondra L]]
[[Category: Zhang, R.]]
[[Category: Zhang R]]
[[Category: Helix barrel]]
[[Category: Mcsg]]
[[Category: Midwest center for structural genomic]]
[[Category: Protein structure initiative]]
[[Category: Psi]]
[[Category: Structural genomic]]
[[Category: Unknown function]]

Latest revision as of 10:55, 14 February 2024

Structure of Protein of Unknown Function of YteR from Bacillus SubtilisStructure of Protein of Unknown Function of YteR from Bacillus Subtilis

Structural highlights

1nc5 is a 1 chain structure with sequence from Bacillus subtilis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.6Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

URHG2_BACSU Catalyzes the hydrolysis of unsaturated rhamnogalacturonan disaccharide to yield unsaturated D-galacturonic acid and L-rhamnose. It cannot act on unsaturated glucuronyl hydrolase (UGL) substrates containing unsaturated D-glucuronic acid at the non-reducing terminus, although the active pockets of YesR and UGL are very similar.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Itoh T, Ochiai A, Mikami B, Hashimoto W, Murata K. A novel glycoside hydrolase family 105: the structure of family 105 unsaturated rhamnogalacturonyl hydrolase complexed with a disaccharide in comparison with family 88 enzyme complexed with the disaccharide. J Mol Biol. 2006 Jul 14;360(3):573-85. Epub 2006 May 9. PMID:16781735 doi:10.1016/j.jmb.2006.04.047

1nc5, resolution 1.60Å

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