1n4j: Difference between revisions

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-{{Seed}}
-[[Image:1n4j.png|left|200px]]
-<!--
+==STREPTAVIDIN MUTANT N23A AT 2.18A==
-The line below this paragraph, containing "STRUCTURE_1n4j", creates the "Structure Box" on the page.
+<StructureSection load='1n4j' size='340' side='right'caption='[[1n4j]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1n4j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N4J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N4J FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.18&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n4j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n4j OCA], [https://pdbe.org/1n4j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n4j RCSB], [https://www.ebi.ac.uk/pdbsum/1n4j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n4j ProSAT]</span></td></tr>
-{{STRUCTURE_1n4j|  PDB=1n4j  |  SCENE=  }}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n4/1n4j_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n4j ConSurf].
+<div style="clear:both"></div>
-===STREPTAVIDIN MUTANT N23A AT 2.18A===
+==See Also==
+*[[Avidin 3D structures|Avidin 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_12925786}}, adds the Publication Abstract to the page
+[[Category: Large Structures]]
-(as it appears on PubMed at http://www.pubmed.gov), where 12925786 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_12925786}}
-==About this Structure==
-N4J is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N4J OCA].
-==Reference==
-Structural studies of hydrogen bonds in the high-affinity streptavidin-biotin complex: mutations of amino acids interacting with the ureido oxygen of biotin., Le Trong I, Freitag S, Klumb LA, Chu V, Stayton PS, Stenkamp RE, Acta Crystallogr D Biol Crystallogr. 2003 Sep;59(Pt 9):1567-73. Epub 2003, Aug 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12925786 12925786]
-[[Category: Single protein]]
 [[Category: Streptomyces avidinii]]
-[[Category: Chu, V.]]
+[[Category: Chu V]]
-[[Category: Freitag, S.]]
+[[Category: Freitag S]]
-[[Category: Klumb, L A.]]
+[[Category: Klumb LA]]
-[[Category: Stayton, P S.]]
+[[Category: Le Trong I]]
-[[Category: Stenkamp, R E.]]
+[[Category: Stayton PS]]
-[[Category: Trong, I Le.]]
+[[Category: Stenkamp RE]]
-[[Category: Homotetramer]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 17:46:53 2008''