1n0f: Difference between revisions

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New page: left|200px<br /><applet load="1n0f" size="450" color="white" frame="true" align="right" spinBox="true" caption="1n0f, resolution 2.80Å" /> '''CRYSTAL STRUCTURE OF...
 
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[[Image:1n0f.gif|left|200px]]<br /><applet load="1n0f" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1n0f, resolution 2.80&Aring;" />
'''CRYSTAL STRUCTURE OF A CELL DIVISION AND CELL WALL BIOSYNTHESIS PROTEIN UPF0040 FROM MYCOPLASMA PNEUMONIAE: INDICATION OF A NOVEL FOLD WITH A POSSIBLE NEW CONSERVED SEQUENCE MOTIF'''<br />


==Overview==
==CRYSTAL STRUCTURE OF A CELL DIVISION AND CELL WALL BIOSYNTHESIS PROTEIN UPF0040 FROM MYCOPLASMA PNEUMONIAE: INDICATION OF A NOVEL FOLD WITH A POSSIBLE NEW CONSERVED SEQUENCE MOTIF==
UPF0040 is a family of proteins implicated in a cellular function of, bacteria cell division. There is no structure information available on, protein of this family. We have determined the crystal structure of a, protein from Mycoplasma pneumoniae that belongs to this family using X-ray, crystallography. Structural homology search reveals that this protein has, a novel fold with no significant similarity to any proteins of known, three-dimensional structure. The crystal structures of the protein in, three different crystal forms reveal that the protein exists as a ring of, octamer. The conserved protein residues, including a highly conserved, DXXXR motif, are examined on the basis of crystal structure.
<StructureSection load='1n0f' size='340' side='right'caption='[[1n0f]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[1n0f]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycoplasma_pneumoniae Mycoplasma pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N0F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N0F FirstGlance]. <br>
1N0F is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycoplasma_pneumoniae Mycoplasma pneumoniae]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1N0F OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n0f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n0f OCA], [https://pdbe.org/1n0f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n0f RCSB], [https://www.ebi.ac.uk/pdbsum/1n0f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n0f ProSAT], [https://www.topsan.org/Proteins/BSGC/1n0f TOPSAN]</span></td></tr>
==Reference==
</table>
Crystal structure of a protein associated with cell division from Mycoplasma pneumoniae (GI: 13508053): a novel fold with a conserved sequence motif., Chen S, Jancrick J, Yokota H, Kim R, Kim SH, Proteins. 2004 Jun 1;55(4):785-91. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15146477 15146477]
== Function ==
[https://www.uniprot.org/uniprot/MRAZ_MYCPN MRAZ_MYCPN]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n0/1n0f_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n0f ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycoplasma pneumoniae]]
[[Category: Mycoplasma pneumoniae]]
[[Category: Single protein]]
[[Category: Chen S]]
[[Category: BSGC, Berkeley.Structural.Genomics.Center.]]
[[Category: Jancrick J]]
[[Category: Chen, S.]]
[[Category: Kim R]]
[[Category: Jancrick, J.]]
[[Category: Kim S-H]]
[[Category: Kim, R.]]
[[Category: Yokota H]]
[[Category: Kim, S.H.]]
[[Category: Yokota, H.]]
[[Category: berkeley structural genomics center]]
[[Category: bsgc structure funded by nih]]
[[Category: cell division]]
[[Category: cell wall biosynthesis protein]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomics]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 21:51:04 2007''

Latest revision as of 10:50, 14 February 2024

CRYSTAL STRUCTURE OF A CELL DIVISION AND CELL WALL BIOSYNTHESIS PROTEIN UPF0040 FROM MYCOPLASMA PNEUMONIAE: INDICATION OF A NOVEL FOLD WITH A POSSIBLE NEW CONSERVED SEQUENCE MOTIFCRYSTAL STRUCTURE OF A CELL DIVISION AND CELL WALL BIOSYNTHESIS PROTEIN UPF0040 FROM MYCOPLASMA PNEUMONIAE: INDICATION OF A NOVEL FOLD WITH A POSSIBLE NEW CONSERVED SEQUENCE MOTIF

Structural highlights

1n0f is a 8 chain structure with sequence from Mycoplasma pneumoniae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.8Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

MRAZ_MYCPN

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1n0f, resolution 2.80Å

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