1n0f: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:1n0f.gif|left|200px]]<br /><applet load="1n0f" size="350" color="white" frame="true" align="right" spinBox="true"
-caption="1n0f, resolution 2.80&Aring;" />
-'''CRYSTAL STRUCTURE OF A CELL DIVISION AND CELL WALL BIOSYNTHESIS PROTEIN UPF0040 FROM MYCOPLASMA PNEUMONIAE: INDICATION OF A NOVEL FOLD WITH A POSSIBLE NEW CONSERVED SEQUENCE MOTIF'''<br />
-==Overview==
+==CRYSTAL STRUCTURE OF A CELL DIVISION AND CELL WALL BIOSYNTHESIS PROTEIN UPF0040 FROM MYCOPLASMA PNEUMONIAE: INDICATION OF A NOVEL FOLD WITH A POSSIBLE NEW CONSERVED SEQUENCE MOTIF==
-UPF0040 is a family of proteins implicated in a cellular function of bacteria cell division. There is no structure information available on protein of this family. We have determined the crystal structure of a protein from Mycoplasma pneumoniae that belongs to this family using X-ray crystallography. Structural homology search reveals that this protein has a novel fold with no significant similarity to any proteins of known three-dimensional structure. The crystal structures of the protein in three different crystal forms reveal that the protein exists as a ring of octamer. The conserved protein residues, including a highly conserved DXXXR motif, are examined on the basis of crystal structure.
+<StructureSection load='1n0f' size='340' side='right'caption='[[1n0f]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
+== Structural highlights ==
-==About this Structure==
+<table><tr><td colspan='2'>[[1n0f]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycoplasma_pneumoniae Mycoplasma pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N0F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N0F FirstGlance]. <br>
-N0F is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycoplasma_pneumoniae Mycoplasma pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N0F OCA].
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n0f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n0f OCA], [https://pdbe.org/1n0f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n0f RCSB], [https://www.ebi.ac.uk/pdbsum/1n0f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n0f ProSAT], [https://www.topsan.org/Proteins/BSGC/1n0f TOPSAN]</span></td></tr>
-==Reference==
+</table>
-Crystal structure of a protein associated with cell division from Mycoplasma pneumoniae (GI: 13508053): a novel fold with a conserved sequence motif., Chen S, Jancrick J, Yokota H, Kim R, Kim SH, Proteins. 2004 Jun 1;55(4):785-91. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15146477 15146477]
+== Function ==
+[https://www.uniprot.org/uniprot/MRAZ_MYCPN MRAZ_MYCPN]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n0/1n0f_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n0f ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Mycoplasma pneumoniae]]
-[[Category: Single protein]]
+[[Category: Chen S]]
-[[Category: BSGC, Berkeley Structural Genomics Center.]]
+[[Category: Jancrick J]]
-[[Category: Chen, S.]]
+[[Category: Kim R]]
-[[Category: Jancrick, J.]]
+[[Category: Kim S-H]]
-[[Category: Kim, R.]]
+[[Category: Yokota H]]
-[[Category: Kim, S H.]]
-[[Category: Yokota, H.]]
-[[Category: berkeley structural genomics center]]
-[[Category: bsgc structure funded by nih]]
-[[Category: cell division]]
-[[Category: cell wall biosynthesis protein]]
-[[Category: protein structure initiative]]
-[[Category: psi]]
-[[Category: structural genomics]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:00:56 2008''