1msk: Difference between revisions

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-{{Seed}}
-[[Image:1msk.png|left|200px]]
-<!--
+==METHIONINE SYNTHASE (ACTIVATION DOMAIN)==
-The line below this paragraph, containing "STRUCTURE_1msk", creates the "Structure Box" on the page.
+<StructureSection load='1msk' size='340' side='right'caption='[[1msk]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1msk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MSK FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
-{{STRUCTURE_1msk|  PDB=1msk  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1msk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1msk OCA], [https://pdbe.org/1msk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1msk RCSB], [https://www.ebi.ac.uk/pdbsum/1msk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1msk ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/METH_ECOLI METH_ECOLI] Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ms/1msk_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1msk ConSurf].
+<div style="clear:both"></div>
-===METHIONINE SYNTHASE (ACTIVATION DOMAIN)===
+==See Also==
+*[[Methionine synthase 3D structures|Methionine synthase 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_8939751}}, adds the Publication Abstract to the page
+[[Category: Escherichia coli K-12]]
-(as it appears on PubMed at http://www.pubmed.gov), where 8939751 is the PubMed ID number.
+[[Category: Large Structures]]
--->
+[[Category: Dixon MM]]
-{{ABSTRACT_PUBMED_8939751}}
+[[Category: Huang S]]
+[[Category: Ludwig ML]]
-==About this Structure==
+[[Category: Matthews RG]]
-MSK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSK OCA].
-==Reference==
-The structure of the C-terminal domain of methionine synthase: presenting S-adenosylmethionine for reductive methylation of B12., Dixon MM, Huang S, Matthews RG, Ludwig M, Structure. 1996 Nov 15;4(11):1263-75. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8939751 8939751]
-[[Category: Escherichia coli]]
-[[Category: Methionine synthase]]
-[[Category: Single protein]]
-[[Category: Dixon, M M.]]
-[[Category: Huang, S.]]
-[[Category: Ludwig, M L.]]
-[[Category: Matthews, R G.]]
-[[Category: Methionine biosynthesis]]
-[[Category: Methyltransferase]]
-[[Category: Transferase]]
-[[Category: Vitamin b12]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 15:58:16 2008''