1mmp: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-{{Seed}}
-[[Image:1mmp.png|left|200px]]
-<!--
+==MATRILYSIN COMPLEXED WITH CARBOXYLATE INHIBITOR==
-The line below this paragraph, containing "STRUCTURE_1mmp", creates the "Structure Box" on the page.
+<StructureSection load='1mmp' size='340' side='right'caption='[[1mmp]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1mmp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MMP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MMP FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=RSS:5-METHYL-3-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18]NONADECA-12(19),13,15,17-TETRAEN-10-YLCARBAMOYL)-HEXANOIC+ACID'>RSS</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-{{STRUCTURE_1mmp|  PDB=1mmp  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mmp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mmp OCA], [https://pdbe.org/1mmp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mmp RCSB], [https://www.ebi.ac.uk/pdbsum/1mmp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mmp ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/MMP7_HUMAN MMP7_HUMAN] Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.<ref>PMID:2550050</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mm/1mmp_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mmp ConSurf].
+<div style="clear:both"></div>
-===MATRILYSIN COMPLEXED WITH CARBOXYLATE INHIBITOR===
+==See Also==
+*[[Matrix metalloproteinase 3D structures|Matrix metalloproteinase 3D structures]]
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_7756291}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 7756291 is the PubMed ID number.
+</StructureSection>
--->
-{{ABSTRACT_PUBMED_7756291}}
-==About this Structure==
-MMP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MMP OCA].
-==Reference==
-Matrilysin-inhibitor complexes: common themes among metalloproteases., Browner MF, Smith WW, Castelhano AL, Biochemistry. 1995 May 23;34(20):6602-10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7756291 7756291]
 [[Category: Homo sapiens]]
-[[Category: Matrilysin]]
+[[Category: Large Structures]]
-[[Category: Single protein]]
+[[Category: Browner MF]]
-[[Category: Browner, M F.]]
+[[Category: Castelhano AL]]
-[[Category: Castelhano, A L.]]
+[[Category: Smith WW]]
-[[Category: Smith, W W.]]
-[[Category: Metalloprotease]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul  3 00:23:55 2008''