1mlh: Difference between revisions

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[[Image:1mlh.png|left|200px]]


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==STRUCTURAL AND FUNCTIONAL EFFECTS OF APOLAR MUTATIONS OF VAL68(E11) IN MYOGLOBIN==
The line below this paragraph, containing "STRUCTURE_1mlh", creates the "Structure Box" on the page.
<StructureSection load='1mlh' size='340' side='right'caption='[[1mlh]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1mlh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MLH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MLH FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_1mlh|  PDB=1mlh |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mlh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mlh OCA], [https://pdbe.org/1mlh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mlh RCSB], [https://www.ebi.ac.uk/pdbsum/1mlh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mlh ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MYG_PHYMC MYG_PHYMC] Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ml/1mlh_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mlh ConSurf].
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===STRUCTURAL AND FUNCTIONAL EFFECTS OF APOLAR MUTATIONS OF VAL68(E11) IN MYOGLOBIN===
==See Also==
 
*[[Myoglobin 3D structures|Myoglobin 3D structures]]
 
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The line below this paragraph, {{ABSTRACT_PUBMED_7837273}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 7837273 is the PubMed ID number.
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{{ABSTRACT_PUBMED_7837273}}
 
==About this Structure==
1MLH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MLH OCA].
 
==Reference==
Structural and functional effects of apolar mutations of the distal valine in myoglobin., Quillin ML, Li T, Olson JS, Phillips GN Jr, Dou Y, Ikeda-Saito M, Regan R, Carlson M, Gibson QH, Li H, et al., J Mol Biol. 1995 Jan 27;245(4):416-36. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7837273 7837273]
[[Category: Physeter catodon]]
[[Category: Physeter catodon]]
[[Category: Single protein]]
[[Category: Phillips Jr GN]]
[[Category: Jr., G N.Phillips.]]
[[Category: Quillin ML]]
[[Category: Quillin, M L.]]
[[Category: Oxygen storage]]
 
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