1mix: Difference between revisions

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[[Image:1mix.png|left|200px]]


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==Crystal structure of a FERM domain of Talin==
The line below this paragraph, containing "STRUCTURE_1mix", creates the "Structure Box" on the page.
<StructureSection load='1mix' size='340' side='right'caption='[[1mix]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1mix]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MIX FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mix FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mix OCA], [https://pdbe.org/1mix PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mix RCSB], [https://www.ebi.ac.uk/pdbsum/1mix PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mix ProSAT]</span></td></tr>
{{STRUCTURE_1mix| PDB=1mix |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/TLN1_CHICK TLN1_CHICK] Probably involved in connections of major cytoskeletal structures to the plasma membrane. Talin is a high molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mi/1mix_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mix ConSurf].
<div style="clear:both"></div>


===Crystal structure of a FERM domain of Talin===
==See Also==
 
*[[Talin 3D structures|Talin 3D structures]]
 
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{{ABSTRACT_PUBMED_12535520}}
 
==About this Structure==
1MIX is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIX OCA].
 
==Reference==
<ref group="xtra">PMID:12535520</ref><references group="xtra"/>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Calderwood, D A.]]
[[Category: Large Structures]]
[[Category: Campbell, I D.]]
[[Category: Calderwood DA]]
[[Category: Critchley, D.]]
[[Category: Campbell ID]]
[[Category: Garcia-Alvarez, B.]]
[[Category: Critchley D]]
[[Category: Ginsberg, M H.]]
[[Category: Garcia-Alvarez B]]
[[Category: Liddington, R C.]]
[[Category: Ginsberg MH]]
[[Category: Pereda, J M.de.]]
[[Category: Liddington RC]]
[[Category: Ulmer, T S.]]
[[Category: Ulmer TS]]
[[Category: Cytoskeleton]]
[[Category: De Pereda JM]]
[[Category: Ferm domain]]
[[Category: Focal adhesion]]
[[Category: Integrin binding]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 09:33:31 2009''

Latest revision as of 10:44, 14 February 2024

Crystal structure of a FERM domain of TalinCrystal structure of a FERM domain of Talin

Structural highlights

1mix is a 1 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.75Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TLN1_CHICK Probably involved in connections of major cytoskeletal structures to the plasma membrane. Talin is a high molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1mix, resolution 1.75Å

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