1mfq: Difference between revisions

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[[Image:1mfq.png|left|200px]]


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==Crystal Structure Analysis of a Ternary S-Domain Complex of Human Signal Recognition Particle==
The line below this paragraph, containing "STRUCTURE_1mfq", creates the "Structure Box" on the page.
<StructureSection load='1mfq' size='340' side='right'caption='[[1mfq]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1mfq]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MFQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MFQ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CCC:CYTIDINE-5-PHOSPHATE-2,3-CYCLIC+PHOSPHATE'>CCC</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_1mfq| PDB=1mfq |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mfq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mfq OCA], [https://pdbe.org/1mfq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mfq RCSB], [https://www.ebi.ac.uk/pdbsum/1mfq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mfq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SRP19_HUMAN SRP19_HUMAN] Signal-recognition-particle assembly, binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mf/1mfq_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mfq ConSurf].
<div style="clear:both"></div>


===Crystal Structure Analysis of a Ternary S-Domain Complex of Human Signal Recognition Particle===
==See Also==
 
*[[Signal recognition particle 3D structures|Signal recognition particle 3D structures]]
 
__TOC__
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</StructureSection>
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{{ABSTRACT_PUBMED_12244299}}
 
==About this Structure==
1MFQ is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MFQ OCA].
 
==Reference==
<ref group="xtra">PMID:12244299</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Kuglstatter, A.]]
[[Category: Large Structures]]
[[Category: Nagai, K.]]
[[Category: Kuglstatter A]]
[[Category: Oubridge, C.]]
[[Category: Nagai K]]
[[Category: 3-helix junction]]
[[Category: Oubridge C]]
[[Category: A-minor motif]]
[[Category: Rna-protein complex]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:15:47 2009''

Latest revision as of 10:43, 14 February 2024

Crystal Structure Analysis of a Ternary S-Domain Complex of Human Signal Recognition ParticleCrystal Structure Analysis of a Ternary S-Domain Complex of Human Signal Recognition Particle

Structural highlights

1mfq is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.1Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SRP19_HUMAN Signal-recognition-particle assembly, binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1mfq, resolution 3.10Å

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