1mfq: Difference between revisions

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-[[Image:1mfq.png|left|200px]]
-{{STRUCTURE_1mfq|  PDB=1mfq  |  SCENE=  }}
+==Crystal Structure Analysis of a Ternary S-Domain Complex of Human Signal Recognition Particle==
+<StructureSection load='1mfq' size='340' side='right'caption='[[1mfq]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
-===Crystal Structure Analysis of a Ternary S-Domain Complex of Human Signal Recognition Particle===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1mfq]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MFQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MFQ FirstGlance]. <br>
-{{ABSTRACT_PUBMED_12244299}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CCC:CYTIDINE-5-PHOSPHATE-2,3-CYCLIC+PHOSPHATE'>CCC</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mfq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mfq OCA], [https://pdbe.org/1mfq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mfq RCSB], [https://www.ebi.ac.uk/pdbsum/1mfq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mfq ProSAT]</span></td></tr>
-[[1mfq]] is a 3 chain structure of [[Signal recognition particle protein]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MFQ OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/SRP19_HUMAN SRP19_HUMAN] Signal-recognition-particle assembly, binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mf/1mfq_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mfq ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Signal recognition particle protein|Signal recognition particle protein]]
+*[[Signal recognition particle 3D structures|Signal recognition particle 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:012244299</ref><ref group="xtra">PMID:014985753</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: Kuglstatter, A.]]
+[[Category: Large Structures]]
-[[Category: Nagai, K.]]
+[[Category: Kuglstatter A]]
-[[Category: Oubridge, C.]]
+[[Category: Nagai K]]
-[[Category: 3-helix junction]]
+[[Category: Oubridge C]]
-[[Category: A-minor motif]]
-[[Category: Rna-protein complex]]
-[[Category: Signaling protein-rna complex]]